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Table of Contents
Vol. 220, No. 2, 2010
Issue release date: March 2010
Section title: Original Paper
Dermatology 2010;220:103–109
(DOI:10.1159/000265556)

Studying Regression of Seborrheic Keratosis in Lichenoid Keratosis with Sequential Dermoscopy Imaging

Zaballos P. · Salsench E. · Serrano P. · Cuellar F. · Puig S. · Malvehy J.
aDepartment of Dermatology, Hospital de Sant Pau i Santa Tecla, Tarragona, and bDepartment of Dermatology, Melanoma Unit, Hospital Clinic, IDIBAPS, Barcelona, Spain

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 8/24/2009
Accepted: 10/21/2009
Published online: 12/9/2009

Number of Print Pages: 7
Number of Figures: 4
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Background: Lichenoid keratosis (LK) is a well-described entity that has been proposed to represent a regressive response to a pre-existent epidermal lesion. Aims: To evaluate the natural evolution of a series of cases showing the intermediate stage of the regression of seborrheic keratosis in LK using sequential dermoscopy imaging over time. Material and Methods: A series of lesions with dermoscopic areas of seborrheic keratosis and LK in the same tumor were consecutively collected for over 3 years at the Dermatology Department of the Hospital de Sant Pau i Santa Tecla, Tarragona, Spain. Sequential dermoscopic images of each case were collected quarterly for 1 year. At the end of the follow-up, all the lesions were biopsied. Results: A total of 22 cases were collected. At the end of the follow-up, the LK part increased in all the lesions. In 11 cases (50%), the seborrheic keratosis part disappeared completely, and in another 5 cases (22.7%), seborrheic keratosis comprised only 10% of the remaining area. Conclusions: These dermoscopic study findings support the proposal that LK represents a regressive response to a pre-existent epidermal lesion, in this case seborrheic keratosis.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 8/24/2009
Accepted: 10/21/2009
Published online: 12/9/2009

Number of Print Pages: 7
Number of Figures: 4
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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