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Vol. 44, No. 1, 2010
Issue release date: March 2010
Section title: Review
Free Access
Caries Res 2010;44:3–13

Sealants in Dentistry: Outcomes of the ORCA Saturday Afternoon Symposium 2007

Splieth C.H.a · Ekstrand K.R.c · Alkilzy M.a · Clarkson J.d · Meyer-Lueckel H.b · Martignon S.f · Paris S.b · Pitts N.B.d · Ricketts D.N.e · van Loveren C.g
aDepartment of Preventive and Pediatric Dentistry, Ernst Moritz Arndt University, Greifswald, and bClinic for Conservative Dentistry and Periodontology, Christian Albrechts University Kiel, Kiel, Germany; cDepartment of Cariology and Endodontics, University of Copenhagen, Copenhagen, Denmark; dDental Health Services Research Unit and eDepartment of Restorative Dental Care and Clinical Dental Sciences, University of Dundee, Dundee, UK; fCaries Research Unit UNICA, Universidad El Bosque, Bogota, Colombia; gCariologie Endodontologie Pedodontologie, Academisch Centrum voor Tandheelkunde Amsterdam, Amsterdam, The Netherlands
email Corresponding Author

Prof. Dr. Christian H. Splieth

Präventive Zahnmedizin und Kinderzahnheilkunde

Rotgerberstrasse 8

DE–17487 Greifswald (Germany)

Tel. +49 3834 867 101, Fax +49 3834 867 299, E-Mail


  1. Ahovuo-Saloranta A, Hiiri A, Nordblad A, Mäkelä M, Worthington HV: Pit and fissure sealants for preventing dental decay in the permanent teeth of children and adolescents. Cochrane Database Syst Rev 2008;4:CD001830.
  2. Alkilzy M, Berndt C, Meller C, Schidlowski M, Splieth CH: Sealing of proximal surfaces with polyurethane tape: a two-year clinical and radiographic feasibility study. J Adhes Dent 2009;11:91–94.
  3. Araujo AM, Naspitz GM, Chelotti A, Cai S: Effect of Cervitec on mutans streptococci in plaque and on caries formation on occlusal fissures of erupting permanent molars. Caries Res 2002;36:373–376.
  4. Beiruti N, Frencken JE, van’t Hof MA, van Palenstein Helderman WH: Caries preventive effect of resin-based and glass ionomer sealants over time: a systematic review. Community Dent Oral Epidemiol 2006;34:403–409.
  5. Bratthall D, Hänsel-Petersson G, Sundberg H: Reasons for the caries decline: what do the experts believe? Eur J Oral Sci 1996;104:416–422, discussion 423–425, 430–432.
  6. Carvalho JC, Ekstrand KR, Thylstrup A: Dental plaque and caries on occlusal surfaces of first permanent molars in relation to stage of eruption. J Dent Res 1989;68:773–779.
  7. Carvalho JC, Ekstrand KR, Thylstrup A: Results after 1 year of non-operative occlusal caries treatment of erupting permanent first molars. Community Dent Oral Epidemiol 1991;19:23–28.
  8. Carvalho JC, Thylstrup A, Ekstrand KR: Results after 3 years of non-operative occlusal caries treatment of erupting permanent first molars. Community Dent Oral Epidemiol 1992;20:187–192.
  9. Davila JM, Buonocore MG, Greeley CB, Provenza DV: Adhesive penetration in human artificial and natural white spots. J Dent Res 1975;54:999–1008.
  10. Donly KJ, Ruiz M: In vitro demineralization inhibition of enamel caries utilizing an unfilled resin. Clin Prev Dent 1992;14:22–24.
  11. Ekstrand KR, Christiansen MEC: Outcome of a non-operative caries treatment programme for children and adolescents. Caries Res 2005;39:455–467.
  12. Ekstrand KR, Christiansen MEC: Nexø-metoden set i et sundhedsfremmende perspektiv. Tandlægebladet 2008;112:112–123.
  13. Ekstrand KR, Martignon S, Christiansen MEC: Frequency and distribution patterns of sealants among 15-year-olds in Denmark in 2003. Community Dent Health 2007a;24:26–30.
  14. Ekstrand KR, Martignon S, Ricketts DJ, Qvist V: Detection and activity assessment of primary coronal caries lesions: a methodologic study. Oper Dent 2007b;32:225–235.
  15. Ekstrand KR, Bakhshandeh A, Martignon S: Treatment of proximal superficial caries lesions on primary molar teeth with resin infiltration and fluoride varnish versus fluoride varnish only: Efficacy after 1 year. Caries Res 2010, in press.
  16. Garçía-Godoy F, Summitt JB, Donly KJ: Caries progression of white spot lesions sealed with an unfilled resin. J Clin Pediatr Dent 1997;21:141–143.

    External Resources

  17. Goepferd SJ, Olberding P: The effect of sealing white spot lesions on lesion progression in vitro. Pediatr Dent 1989;11:14–16.
  18. Gomez SS, Basili CP, Emilson CG: A 2-year clinical evaluation of sealed noncavitated approximal posterior carious lesions in adolescents. Clin Oral Invest 2005;9:239–243.
  19. Gray GB, Shellis RP: Infiltration of resin into white spot caries-like lesions of enamel: an in vitro study. Eur J Prosthodont Restor Dent 2002;10:27–32.

    External Resources

  20. Griffin SO, Oong E, Kohn W, Vidakovic B, Gooch BF; CDC Dental Sealant Systematic Review Group; Bader J, Clarkson J, Fontana MR, Meyer DM, Rozier RG, Weintraub JA, Zero DT: The effectiveness of sealants in managing caries lesions. J Dent Res 2008;87:169–174.
  21. Heyduck C, Meller C, Schwahn C, Splieth CH: Effectiveness of sealants in adolescents with high and low caries experience. Caries Res 2006;40:375–381.
  22. Hiiri A, Ahovuo-Saloranta A, Nordblad A, Mäkelä M: Pit and fissure sealants versus fluoride varnishes for preventing dental decay in children and adolescents. Cochrane Database Syst Rev 2006;4:CD003067.
  23. Innes NP, Evans DJ, Stirrups DR: The Hall Technique: a randomized controlled clinical trial of a novel method of managing carious primary molars in general dental practice: acceptability of the technique and outcomes at 23 months. BMC Oral Health 2007;7:18.
  24. Ismail AI, Sohn W, Tellez M, Amaya A, Sen A, Hasson H, Pitts NB: The International Caries Detection and Assessment System (ICDAS): an integrated system for measuring dental caries. Community Dent Oral Epidemiol 2007;35:170–178.
  25. Jensen OE, Handelman SL: Effect of an autopolymerising sealant on viability of microflora in occlusal dental caries. Scand J Dent Res 1980;88:382–388.
  26. Kidd EA, Fejerskov O: What constitutes dental caries? Histopathology of carious enamel and dentin related to the action of cariogenic biofilms. J Dent Res 2004;83(special issue C):C35–C38.
  27. Marinho VC, Higgins JP, Logan S, Sheiham A: Fluoride gels for preventing dental caries in children and adolescents. Cochrane Database Syst Rev 2002;2:CD002280.
  28. Marinho VC, Higgins JP, Sheiham A, Logan S: Fluoride toothpastes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev 2003;1:CD002278.
  29. Marthaler TM, O’Mullane DM, Vrbic V: The prevalence of dental caries in Europe 1990–1995. ORCA Saturday Afternoon Symposium 1995. Caries Res 1996;30:237–255.
  30. Martignon S, Chavarria N, Ekstrand KR: Caries status and proximal lesion behaviour during a 6-year period in young adult Danes: an epidemiological investigation. Clin Oral Investig DOI: 10.1007/s00784-009-0306-0.

    External Resources

  31. Martignon S, Ekstrand K, Ellwood R: Efficacy of sealing proximal early active lesions: an 18-month clinical study evaluated by conventional and subtraction radiography. Caries Res 2006;40:382–388.
  32. McDonald SP, Sheiham A: The distribution of caries on different tooth surfaces at varying levels of caries – a compilation of data from 18 previous studies. Community Dent Health 1992;9:39–48.
  33. Mejàre I, Källestål C, Stenlund H: Incidence and progression of approximal caries from 11 to 22 years of age in Sweden: a prospective radiographic study. Caries Res 1999;33:93–100.
  34. Mejàre I, Källestål C, Stenlund H, Johansson H: Caries development from 11 to 22 years of age: a prospective radiographic study. Prevalence and distribution. Caries Res 1998;32:10–16.
  35. Mejàre I, Lingström P, Petersson LG, Holm AK, Twetman S, Källestål C, Nordenram G, Lagerlöf F, Söder B, Norlund A, Axelsson S, Dahlgren H: Caries-preventive effect of fissure sealants: a systematic review. Acta Odontol Scand 2003;61:321–330.
  36. Mejàre I, Stenlund H, Zelezny-Holmlund C: Caries incidence and lesion progression from adolescence to young adulthood: a prospective 15-year cohort study in Sweden. Caries Res 2004;38:130–141.
  37. Mertz-Fairhurst EJ, Curtis JW Jr, Ergle JW, Rueggeberg FA, Adair SM: Ultraconservative and cariostatic sealed restorations: results at year 10. J Am Dent Assoc 1998;129:55–66.
  38. Meyer-Lueckel H, Mueller J, Paris S, Hummel M, Kielbassa AM: Penetration verschiedener Adhäsive in initialen Schmelzläsionen in vitro. Schweiz Monatsschr Zahnmed 2005;115:316–323.
  39. Meyer-Lueckel H, Paris S: Improved resin infiltration of caries lesions. J Dent Res 2008a;87:1112–1116.
  40. Meyer-Lueckel H, Paris S: Progression of artificial enamel caries lesions after infiltration with experimental light curing resins. Caries Res 2008b;42:122–128.

    External Resources

  41. Meyer-Lueckel H, Paris S, Kielbassa AM: Surface layer erosion of natural caries lesions with phosphoric and hydrochloric acid gels. Caries Res 2007;41:223–230.
  42. Mueller J, Meyer-Lueckel H, Paris S, Hopfenmuller W, Kielbassa AM: Inhibition of lesion progression by penetration of resins in vitro: influence of the application procedure. Oper Dent 2006;31:339–346.

    External Resources

  43. Oong EM, Griffin SO, Kohn WG, Gooch BF, Caufield PW: The effect of dental sealants on bacteria levels in caries lesions: a review of the evidence. J Am Dent Assoc 2008;139:271–278.
  44. Paris S, Hopfenmuller W, Meyer-Lueckel H: Resin infiltration of caries lesions: an efficacy randomized trial. J Dent Res 2009 (submitted).
  45. Paris S, Meyer-Lueckel H, Colfen H, Kielbassa AM: Resin infiltration of artificial enamel caries lesions with experimental light curing resins. Dent Mater J 2007a;26:582–588.
  46. Paris S, Meyer-Lueckel H, Kielbassa AM: Resin infiltration of natural caries lesions. J Dent Res 2007b;86:662–666.
  47. Paris S, Meyer-Lueckel H, Mueller J, Hummel M, Kielbassa AM: Progression of sealed initial bovine enamel lesions under demineralizing conditions in vitro. Caries Res 2006;40:124–129.
  48. Ricketts DN, Ekstrand KR, Martignon S, Ellwood R, Alatsaris M, Nugent Z: Accuracy and reproducibility of conventional radiographic assessment and subtraction radiography in detecting demineralization in occlusal surfaces. Caries Res 2007;41:121–128.
  49. Ricketts DN, Kidd EA, Innes N, Clarkson J: Complete or ultraconservative removal of decayed tissue in unfilled teeth. Cochrane Database Syst Rev 2006;3:CD003808.
  50. Robinson C, Brookes SJ, Kirkham J, Wood SR, Shore RC: In vitro studies of the penetration of adhesive resins into artificial caries-like lesions. Caries Res 2001;35:136–141.
  51. Robinson C, Hallsworth AS, Weatherell JA, Kunzel W: Arrest and control of carious lesions: a study based on preliminary experiments with resorcinol-formaldehyde resin. J Dent Res 1976;55:812–818.
  52. Rodda JC: Impregnation of caries-like lesions with dental resins. N Z Dent J 1983;79:114–117.
  53. Salar DV, García-Godoy F, Flaitz CM, Hicks MJ: Potential inhibition of demineralization in vitro by fluoride-releasing sealants. J Am Dent Assoc 2007;138:502–506.
  54. Schmidlin PR, Göhring TN, Roos M, Zehnder M: Wear resistance and surface roughness of a newly devised adhesive patch for sealing smooth enamel surfaces. Oper Dent 2006a;31:115–121.
  55. Schmidlin PR, Klück I, Zimmermann J, Roulet JF, Seemann R: Caries-preventive potential of an adhesive patch after thermomechanical loading: a microbial-based in vitro study. J Adhes Dent 2006b;8:7–12.
  56. Schmidlin PR, Zehnder M, Pasqualetti T, Imfeld T, Besek MJ: Penetration of a bonding agent into de- and remineralized enamel in vitro. J Adhes Dent 2004;6:111–115.
  57. Schmidlin PR, Zehnder M, Zimmermann MA, Zimmermann J, Roos M, Roulet JF: Sealing smooth enamel surfaces with a newly devised adhesive patch: a radiochemical in vitro analysis. Dent Mater 2005;21:545–550.
  58. Schwartz M, Gröndahl H-G, Pliskin S, Boffa J: A longitudinal analysis from bite-wing radiographs of the rate of progression of approximal carious lesions through human dental enamel. Arch Oral Biol 1984;29:529–536.
  59. Tagami J, Hosoda H, Fusayama T: Optimal techniques of etching enamel. Oper Dent 1988;13:181–184.
  60. Tanaka M, Matsunaga K, Kadoma Y: Use of fluoride-containing sealant on proximal surfaces. J Med Dent Sci 2000;47:49–53.
  61. WHO: Caries for 12-year-olds by country/area. WHO, 2003.