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Vol. 115, No. 3, 2010
Issue release date: April 2010
Cardiology 2010;115:174–175

Induction of Tolerance to Warfarin after Anaphylaxis with a Desensitization Protocol

Jameson T. · Siri D.
Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, Ill., USA

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Warfarin hypersensitivity is exceedingly rare. A 59-year-old male with acute renal infarction and a history of allergy to warfarin underwent evaluation, confirming presence of warfarin hypersensitivity. Induction of tolerance to warfarin was successfully completed using an oral desensitization protocol, which has not previously been reported.

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