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Table of Contents
Vol. 220, No. 3, 2010
Issue release date: April 2010
Section title: Case and Review
Dermatology 2010;220:254–258
(DOI:10.1159/000278349)

Dowling-Degos Disease: Case Report and Review of the Literature

Batycka-Baran A. · Baran W. · Hryncewicz-Gwozdz A. · Burgdorf W.
aDepartment of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland; bDepartment of Dermatology, Ludwig Maximilian University, Munich, Germany

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Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 10/22/2009
Accepted: 1/18/2010
Published online: 3/20/2010

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Dowling-Degos disease (DDD) is an unusual pigmentary disorder usually caused by mutations in keratin 5. A 44-year-old woman in good general health presented due to the recent appearance of numerous pigmented macules on her axillary and anogenital skin. A biopsy showed lacy, finger-like epidermal extensions into the dermis which were heavily pigmented and associated with tiny cysts or dilated follicles. We view DDD as part of a spectrum of disorders which are morphologically related but vary in location and time of expression. In addition, both the clinical and histological differential diagnostic considerations are extensive.


Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 10/22/2009
Accepted: 1/18/2010
Published online: 3/20/2010

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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