Table of Contents
To view the fulltext, log-in or choose pay-per-view options:
Get Access

Regular Daily Intake of Black Tea Improves Oxidative Stress Biomarkers and Decreases Serum C-Reactive Protein Levels in Type 2 Diabetic Patients

Neyestani T.R. · Shariatzade N. · Kalayi A. · Gharavi A. · Khalaji N. · Dadkhah M. · Zowghi T. · Haidari H. · Shab-bidar S.
Laboratory of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition and Food Technology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran Ann Nutr Metab 2010;57:40–49 (DOI:10.1159/000312666)

Abstract

Background: This study was undertaken to evaluate the possible effects of different daily doses of black tea intake on certain oxidative stress, inflammatory and metabolic biomarkers in patients with type 2 diabetes mellitus (T2DM). Methods: Forty-six patients with known T2DM were randomly assigned either to the test (n = 23, 57.0 ± 7.9 years) or the control (n = 23, 55.4 ± 8.3 years) group. Following a one-week ‘run-in’ period, the test group received 150, 300, 450 and 600 ml of black tea extract (BTE) during the weeks 1, 2, 3 and 4, respectively. The control group received 150 ml BTE a day throughout the intervention period. Dietary, anthropometric and biochemical assessments were performed at the end of each week. Findings: Serum total antioxidant capacity was enhanced similarly in both test and control groups. However, daily intake of 2 cups of BTE by the test group showed a suppressing effect on serum malondialdehyde. Serum C-reactive protein significantly decreased and glutathione levels increased following the intake of 4 cups (600 ml) of BTE a day. Conclusion: Regular intake of BTE had anti-oxidative and anti-inflammatory effects in patients with T2DM. These findings may, to some extent, explain the mechanisms underlying the protective effects of drinking tea against cardiovascular disease.

 

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.


Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50