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Med Princ Pract 2010;19:485–489

Brugada Syndrome with Aborted Sudden Cardiac Death Related to Liquorice-Induced Hypokalemia

Yorgun H.a · Aksoy H.a · Şendur M.A.b · Ateş A.H.a · Kaya E.B.a · Aytemir K.a · Oto A.a
Departments of aCardiology and bInternal Medicine, Hacettepe University, Ankara, Turkey
email Corresponding Author

 goto top of outline Key Words

  • Brugada syndrome
  • Cardiac arrest
  • Liquorice
  • Hypokalemia

 goto top of outline Abstract

Objective: It was the aim of this study to report an aborted cardiac arrest due to ventricular fibrillation and electrocardiographic changes consistent with Brugada syndrome due to liquorice-induced hypokalemia. Clinical Presentation and Intervention: Ventricular fibrillation was witnessed in a 50-year-old woman who was admitted to our emergency department with a history of liquorice ingestion, a herbal product. After stopping liquorice ingestion, the Brugada-like electrocardiographic pattern changed progressively with potassium replacement. A diagnosis of Brugada syndrome was made after the ajmaline challenge test. The patient was discharged with an implantable cardioverter defibrillator and had an uneventfull follow-up. Conclusion: This report illustrates the importance of the investigation for herbal medications in the detailed history of a patient in the cases of electrolyte disturbances and the potential role of hypokalemia in the induction of malignant arrhythmia in Brugada syndrome.

Copyright © 2010 S. Karger AG, Basel

 goto top of outline References
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    External Resources

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 goto top of outline Author Contacts

Hikmet Yorgun, MD
Department of Cardiology
Hacettepe University Faculty of Medicine
TR–06100 Sıhhıye, Ankara (Turkey)
Tel. +90 312 305 1780, Fax +90 312 305 4137, E-Mail

 goto top of outline Article Information

Received: December 15, 2009
Revised: April 6, 2010
Published online: September 28, 2010
Number of Print Pages : 5
Number of Figures : 3, Number of Tables : 0, Number of References : 13

 goto top of outline Publication Details

Medical Principles and Practice (International Journal of the Kuwait University Health Sciences Centre)

Vol. 19, No. 6, Year 2010 (Cover Date: September 2010)

Journal Editor: Owunwanne A. (Kuwait)
ISSN: 1011-7571 (Print), eISSN: 1423-0151 (Online)

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