We show that hemolymph clotting protects Drosophila melanogaster against infections with an entomopathogenic nematode and its symbiotic bacterium. We also provide biochemical and genetic evidence for an involvement of eicosanoids in the same infection model. Taken together, our results confirm the conserved nature of the immune function of clot formation.
© 2010 S. Karger AG, Basel
- Drosophila melanogaster
- Entomopathogenic nematodes
- Heterorhabditis bacteriophora
- Photorhabdus luminescens
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Dr. Ulrich Theopold
Department of Molecular Biology and Functional Genomics
University of Stockholm
SE–10691 Stockholm (Sweden)
Tel. +46 816 4181, Fax +46 816 6488, E-Mail firstname.lastname@example.org
Received: June 23, 2010
Accepted after revision: August 18, 2010
Published online: October 16, 2010
Number of Print Pages : 6
Number of Figures : 3, Number of Tables : 0, Number of References : 26
Journal of Innate Immunity
Vol. 3, No. 1, Year 2011 (Cover Date: December 2010)
Journal Editor: Herwald H. (Lund), Egesten A. (Lund)
ISSN: 1662-811X (Print), eISSN: 1662-8128 (Online)
For additional information: http://www.karger.com/JIN
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