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Multiple Basal Cell Carcinomas after Long-Term Exposure to Hydrazine: Case Report and Review of the Literature

Aigner B.A.a · Darsow U.a · Grosber M.a · Ring J.a · Plötz S.G.b
aDepartment of Dermatology and Allergy am Biederstein, Technical University Munich, Division of Environmental Dermatology and Allergy, Helmholtz Center, TUM, and bDermatology Munich-Harlaching, Munich, Germany Dermatology 2010;221:300–302 (DOI:10.1159/000321338)


Hydrazine (N2H4) is a clear, inorganic colourless liquid. It is known to be a skin sensitizer, a corrosive agent and it causes dermatitis on contact. Hydrazine is employed in chemical plants, used as a corrosion inhibitor for feed waters and may be added to rocket fuels. The authors report the case of a 68-year-old man with multiple basal cell carcinomas (BCCs) covering his arms and face. The patient worked in a steam power plant with extensive exposure to hydrazine for a period of over 10 years. The present case report strongly suggests that there may be a correlation between the long-term exposure to hydrazine and an increased risk for multiple BCCs.


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