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Bilateral Globus Pallidus Internus Deep Brain Stimulation for DYT1+ Generalized Dystonia with Previously Received Bilateral Thalamotomy and Unilateral Pallidotomy

Kim J.P. · Chang W.S. · Park Y.S. · Chang J.W.
Department of Neurosurgery, Severance Hospital, Brain Korea 21 Project for Medical Science, Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea Stereotact Funct Neurosurg 2011;89:205–209 (DOI:10.1159/000325660)


Ablation of the globus pallidus internus (GPi) and thalamotomy have been extensively used in the past. Posteroventral GPi deep brain stimulation has been considered as a treatment for dystonia. However, to date, there is no report in the literature of any dystonia patient who underwent GPi deep brain stimulation who had previously undergone staged bilateral thalamotomy and unilateral pallidotomy. The authors of the present study have acquired relatively good clinical results, even in patients who previously received bilateral thalamotomy and unilateral pallidotomy for DYT1+ primary generalized dystonia.


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