Clinical Laboratory Implementation of Cytogenomic MicroarraysSouth S.T. · Brothman A.R.
Departments of Pediatrics, Human Genetics and Pathology, ARUP Institute for Clinical and Experimental Pathology, ARUP Laboratories, University of Utah School of Medicine, Salt Lake City, Utah, USA Cytogenet Genome Res 2011;135:203–211 (DOI:10.1159/000331425)
Examination of the whole genome for copy number alterations by microarray is now routinely done in many laboratories. The field of cytogenetics has evolved to adapt this technology, and the current phase of transition has resulted in the need for standardization in methodologies and interpretation of data. This review will outline some of the changes addressed in the field over the last several years and briefly discuss some of the trends in data processing, analysis and interpretation.
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