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Vol. 32, No. 3, 2011
Issue release date: December 2011
Section title: Original Research Article
Dement Geriatr Cogn Disord 2011;32:202–208
(DOI:10.1159/000333072)

Early and Presenting Symptoms of Dementia with Lewy Bodies

Auning E. · Rongve A. · Fladby T. · Booij J. · Hortobágyi T. · Siepel F.J. · Ballard C. · Aarsland D.
Departments of aGeriatric Psychiatry and bNeurology, Akershus University Hospital, Lorenskog, cDepartment of Psychiatry, Haugesund Hospital, Haugesund, and dDepartment of Geriatric Psychiatry, Psychiatric Clinic, Stavanger University Hospital, Stavanger, Norway; eDepartment of Nuclear Medicine, University of Amsterdam, Academic Medical Center, Amsterdam, The Netherlands; fDepartment of Clinical Neuroscience, Institute of Psychiatry, and gWolfson Centre for Age-Related Diseases, King’s College London, London, UK; hNVS Department, KI Alzheimer Disease Research Center, Karolinska Institutet, Novum, Stockholm, Sweden; iDepartment of Neuropathology, Institute of Pathology, University of Debrecen, Debrecen, Hungary; jUniversity of Oslo, Ahus Campus, Oslo, Norway

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Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: 9/6/2011
Published online: 11/16/2011

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 3

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM

Abstract

Background/Aims: To explore the presenting and early symptoms of dementia with Lewy bodies (DLB). Method: Patients with mild dementia fulfilling diagnostic criteria for DLB (n = 61) and Alzheimer’s disease (AD) (n = 109) were recruited from outpatient dementia clinics in western Norway. At diagnosis, caregivers were asked which symptom had been the presenting symptom of dementia. Results: Caregivers reported that memory impairment was the most common presenting symptom in DLB (57%), followed by visual hallucinations (44%), depression (34%), problem solving difficulties (33%), gait problems (28%), and tremor/stiffness (25%). In contrast, 99% of AD carers reported impaired memory as a presenting symptom, whereas visual hallucinations were a presenting symptom in 3% of the AD cases. Conclusion: DLB should be suspected in predementia cases with visual hallucinations.


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Accepted: 9/6/2011
Published online: 11/16/2011

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 3

ISSN: 1420-8008 (Print)
eISSN: 1421-9824 (Online)

For additional information: http://www.karger.com/DEM


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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