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Comorbidities Related to BMI Category in Children and Adolescents: German/Austrian/Swiss Obesity Register APV Compared to the German KiGGS Study

Flechtner-Mors M.a · Thamm M.b · Wiegand S.c · Reinehr T.d · Schwab K.O.e · Kiess W.f · Widhalm K.g · Holl R.W.a · for the APV initiative and the BMBF Competence Network Obesity
aInstitute of Epidemiology and Medical Biometry, University of Ulm, Ulm, bRobert Koch Institute, and cCharité Children's Hospital, Humboldt University Berlin, Berlin, dDepartment of Pediatric Endocrinology, Diabetes and Nutrition Medicine, University of Witten/Herdecke, Witten/Herdecke, eDepartment of Pediatrics and Adolescent Medicine, University Hospital, Freiburg, and fUniversity Hospital for Children and Adolescents, Leipzig, Germany; gDepartment of Pediatrics, University of Vienna, Vienna, Austria Horm Res Paediatr 2012;77:19-26 (DOI:10.1159/000334147)


Purpose: To assess cardiovascular risk factors in overweight or obese children and adolescents in Germany, Austria and Switzerland and to investigate the relationship to BMI category. Methods: Data of 63,025 overweight or obese patients (APV population) were compared to normal-weight subjects from a representative study on health status of 14,298 children and adolescents in Germany (KiGGS survey). The weight status was assessed by BMI, and BMI-SDS values were cal-culated using national reference data. Results: In normal-weight KiGGS subjects, mean BMI was 17.3 ± 2.5 (BMI-SDS -0.1 ± 0.8). In the overweight or obese APV population, mean BMI was 30.2 ± 5.6 (BMI-SDS 2.5 ± 0.6). In normal-weight subjects blood pressure, total cholesterol, LDL-cholesterol, and triglycerides were elevated in 6.1, 8.6, 7.0 and 3.0%, respectively, and HDL-cholesterol was reduced in 3.0%, whereas in overweight/obese subjects the percentages of abnormal values were 35.3, 13.8, 14.5, 13.6, and 10.1%, respectively. Conclusions: Cardiovascular risk is increased in obese children and adolescents. There is a strong need to monitor blood pressure and serum lipids in this group of patients. Our results emphasize the importance of prevention of obesity in order to reduce cardiovascular risk.


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