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Vol. 68, No. 1, 2012
Issue release date: July 2012
Section title: Original Paper
Eur Neurol 2012;68:34–41
(DOI:10.1159/000335589)

Picture Agnosia as a Characteristic of Posterior Cortical Atrophy

Sugimoto A. · Midorikawa A. · Koyama S. · Futamura A. · Hieda S. · Kawamura M.
aDepartment of Neurology, Showa University School of Medicine, bDepartment of Psychology, Faculty of Letters, Chuo University, Tokyo, and cDepartment of Design Science, Graduate School of Engineering, Chiba University, Chiba, Japan

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 7/7/2011 8:58:29 AM
Accepted: 12/4/2011
Published online: 6/15/2012

Number of Print Pages: 8
Number of Figures: 8
Number of Tables: 2

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE

Abstract

Background: Posterior cortical atrophy (PCA) is a degenerative disease characterized by progressive visual agnosia with posterior cerebral atrophy. We examine the role of the picture naming test and make a number of suggestions with regard to diagnosing PCA as atypical dementia. Methods: We investigated 3 cases of early-stage PCA with 7 control cases of Alzheimer disease (AD). The patients and controls underwent a naming test with real objects and colored photographs of familiar objects. We then compared rates of correct answers. Results: Patients with early-stage PCA showed significant inability to recognize photographs compared to real objects (F = 196.284, p = 0.0000) as measured by analysis of variants. This difficulty was also significant to AD controls (F = 58.717, p = 0.0000). Conclusion: Picture agnosia is a characteristic symptom of early-stage PCA, and the picture naming test is useful for the diagnosis of PCA as atypical dementia at an early stage.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 7/7/2011 8:58:29 AM
Accepted: 12/4/2011
Published online: 6/15/2012

Number of Print Pages: 8
Number of Figures: 8
Number of Tables: 2

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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