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Table of Contents
Vol. 224, No. 1, 2012
Issue release date: May 2012
Section title: Case and Review
Dermatology 2012;224:15–19
(DOI:10.1159/000337209)

Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review

Zaharia D. · Kanitakis J.
Department of Dermatology and Laboratory of Dermatopathology, Edouard Herriot Hospital Group, Lyon, France

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Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 11/29/2011 11:43:26 AM
Accepted: 1/31/2012
Published online: 3/28/2012

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Eruptive vellus hair cysts (EVHC) are rather uncommon lesions, of which 222 cases have been published in the literature. Their etiopathogenesis is poorly known. We report herein a new typical case of EVHC that was studied immunohistochemically. A 15-year-old male presented with a 4-year history of progressively developing small brown-gray papules on the trunk and extremities. Microscopically the lesions consisted of small epidermoid cysts containing vellus hairs. Immunohistochemically, the lesions expressed keratin 1/10, calretinin and p63 but no epithelial membrane antigen, filaggrin or androgen receptors. A review of the relevant literature shows that EVHC may be inherited or acquired and may be associated to other genodermatoses, namely sebocystomatosis. They could be due to hamartomatous follicular growth, to a trouble in infundibular keratinization leading to vellus hair follicle occlusion, or represent an example of acquired hamartoma. Although benign, this condition is difficult to treat.


Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 11/29/2011 11:43:26 AM
Accepted: 1/31/2012
Published online: 3/28/2012

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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