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Two-Stage Extreme Phenotype Sequencing Design for Discovering and Testing Common and Rare Genetic Variants: Efficiency and PowerKang G.a, c · Lin D.a · Hakonarson H.b · Chen J.a
aDepartment of Biostatistics and Epidemiology, University of Pennsylvania, and bCenter for Applied Genomics, The Joseph Stokes Jr. Research Institute, The Children’s Hospital of Philadelphia, Philadelphia, Pa., and cDepartment of Biostatistics, St. Jude Children’s Research Hospital, Memphis, Tenn., USA Corresponding Author
Jinbo Chen, PhD
Department of Biostatistics and Epidemiology
University of Pennsylvania Perelman School of Medicine
Philadelphia, PA 19104 (USA)
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