Cover

Acute Topics in Sport Nutrition

Editor(s): Lamprecht M. (Graz) 
Table of Contents
Vol. 59, 2012
Section title: Selected Off-Mainstream Sport Supplements
Lamprecht M (ed): Acute Topics in Sport Nutrition. Med Sport Sci. Basel, Karger, 2012, vol 59, pp 29–35
(DOI:10.1159/000342062)

Dietary Nitrate and O2 Consumption during Exercise

Jones A.M. · Bailey S.J. · Vanhatalo A.
Sport and Health Sciences, College of Life and Environmental Sciences, St. Luke’s Campus, University of Exeter, Exeter, UK

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Article / Publication Details

First-Page Preview
Abstract of Selected Off-Mainstream Sport Supplements

Published online: 10/15/2012
Cover Date: 2012

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 0

ISBN: 978-3-8055-9992-4 (Print)
eISBN: 978-3-8055-9993-1 (Online)

Abstract

Recent studies have investigated the influence of dietary nitrate supplementation on the physiological responses to exercise. Specifically, it has been reported that enhancing nitric oxide (NO) bioavailability through supplementation of the diet with nitrate salts or nitrate-rich beetroot juice reduces the O2 cost of exercise and improves exercise performance. The lower O2 cost for a given sub-maximal work rate following nitrate ingestion indicates that muscle efficiency is enhanced either as a consequence of a reduced energy cost of contraction or enhanced mitochondrial efficiency. The positive effects of nitrate supplementation on the O2 cost of sub-maximal exercise can be manifested acutely (i.e. 2.5 h following ingestion) and maintained for at least 15 days if supplementation is continued. Most recently, the influence of dietary nitrate supplementation on time trial performance in competitive cyclists has been investigated. Studies have shown a 1–2% reduction in the time to complete time trial distances between 4 and 16 km. The dose of nitrate that has been shown to improve exercise efficiency can readily be achieved through the consumption of 0.5 litre of beetroot juice or an equivalent high-nitrate foodstuff. Following a 5- to 6-mmol bolus of nitrate, plasma [nitrite] typically peaks within 2–3 h and remains elevated for a further 6–9 h before declining towards baseline. Therefore, consuming nitrate approximately 3 h prior to competition or training is recommended if athletes wish to explore the ergogenic potential of nitrate supplementation.


Article / Publication Details

First-Page Preview
Abstract of Selected Off-Mainstream Sport Supplements

Published online: 10/15/2012
Cover Date: 2012

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 0

ISBN: 978-3-8055-9992-4 (Print)
eISBN: 978-3-8055-9993-1 (Online)


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Larsen FJ, Weitzberg E, Lundberg JO, Ekblom B: Effects of dietary nitrate on oxygen cost during exercise. Acta Physiol 2007;191:59-66
  2. Larsen FJ, Weitzberg E, Lundberg JO, Ekblom B: Dietary nitrate reduces maximal oxygen consumption while maintaining work performance in maximal exercise. Free Radic Biol Med 2010;48:342-347
  3. Bailey SJ, Winyard P, Vanhatalo A, Blackwell JR, DiMenna FJ, Wilkerson DP, Tarr J, Benjamin N, Jones AM: Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. J Appl Physiol 2009;107:1144-1155
  4. Bailey SJ, Fulford J, Vanhatalo A, Winyard P, Blackwell JR, DiMenna FJ, Wilkerson DP, Benjamin N, Jones AM: Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans. J Appl Physiol 2010;109:135-148
  5. Vanhatalo A, Bailey SJ, Blackwell JR, DiMenna FJ, Pavey TG, Wilkerson DP, Benjamin N, Winyard PG, Jones AM: Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise. Am J Physiol Regul Integr Comp Physiol 2010;299:R1121-1131
  6. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ, Ahluwalia A: Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension 2008;51:784-790
  7. Lansley KE, Winyard PG, Fulford J, Vanhatalo A, Bailey SJ, Blackwell JR, DiMenna FJ, Gilchrist M, Benjamin N, Jones AM: Dietary nitrate supplementation reduces the O2 cost of walking and running: a placebo-controlled study. J Appl Physiol 2011;110:591-600
  8. Mahler M: First-order kinetics of muscle oxygen consumption, and equivalent proportionality between Qo2 and phosphorylcreatine level. Implications for the control of respiration. J Gen Physiol 1985;86:135-165
  9. Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E: Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab 2011;13:149-159
  10. Vanhatalo A, Fulford J, Bailey SJ, Blackwell JR, Winyard PG, Jones AM: Dietary nitrate reduces muscle metabolic perturbation and improves exercise tolerance in hypoxia. J Physiol 2011;589:5517-5528
  11. Kenjale AA, Ham KL, Stabler T, Robbins JL, Johnson JL, Vanbruggen M, Privette G, Yim E, Kraus WE, Allen JD: Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease. J Appl Physiol 2011;110:1582-1591
  12. Hopkins WG, Hawley JA, Burke LM: Design and analysis of research on sport performance enhancement. Med Sci Sports Exerc 1999;31:472-485
  13. Lansley KE, Winyard PG, Bailey SJ, Vanhatalo A, Wilkerson DP, Blackwell JR, Gilchrist M, Benjamin N, Jones AM: Acute dietary nitrate supplementation improves cycling time trial performance. Med Sci Sports Exerc 2011;43:1125-1131
  14. Cermak NM, Gibala MJ, van Loon LJ: Nitrate supplementation's improvement of 10-km time-trial performance in trained cyclists. Int J Sport Nutr Exerc Metab 2012;22:64-71
  15. Wilkerson DP, Hayward GM, Bailey SJ, Vanhatalo A, Blackwell JR, Jones AM: Influence of acute dietary nitrate supplementation on 50 mile time trial performance in well-trained cyclists. Eur J Appl Physiol 2012;Apr20in press