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Vol. 124, No. 1, 2013
Issue release date: January 2013
Cardiology 2013;124:25–27
(DOI:10.1159/000346031)

Sluggish Left Atria Predecessor to Stroke in CKD: Cause or Effect?

Saggi S.J. · Salifu M.O.
Downstate Medical Center, State University of New York, New York, N.Y., USA

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Abstract of Editorial Comment

Copyright / Drug Dosage

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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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References

  1. Foley RN, et al: Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol 1998;9(12 suppl):S16–S23.
  2. Olesen JB, et al: Stroke and bleeding in atrial fibrillation with chronic kidney disease. N Engl J Med 2012;367:625–635.
  3. Arboix A, et al: Atrial fibrillation and stroke: clinical presentation of cardioembolic versus atherothrombotic infarction. Int J Cardiol 2000;73:33–42.
  4. Ellis K, et al: Transthoracic echocardiographic predictors of left atrial appendage thrombus. Am J Cardiol 2006;97:421–425.
  5. Yarmohammadi H, et al: Role of CHADS2 score in evaluation of thromboembolic risk and mortality in patients with atrial fibrillation undergoing direct current cardioversion (from the ACUTE Trial Substudy). Am J Cardiol 2012;110:222–226.
  6. Providência R, Fernandes A, Paiva L, Faustino A, Barra S, Botelho A, Trigo J, Nascimento J, Leitão-Marquez A: Decreased glomerular filtration rate and markers of left atrial stasis in patients with nonvalvular atrial fibrillation. Cardiology 2013;124:3–10.

    External Resources

  7. Matsushita K, Tonelli M, Lloyd A, Levey AS, Coresh J, Hemmelgarn BR, Alberta Kidney Disease Network: Clinical risk implications of the CKD Epidemiology Collaboration (CKD-EPI) equation compared with the Modification of Diet in Renal Disease (MDRD) Study equation for estimated GFR. Am J Kidney Dis 2012;60:241–249.
  8. Singh AK, et al: Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006;355:2085–2098.
  9. Gordis L: Epidemiology: 2004, Case Control and Cross sectional studies, p 173–175.
  10. Edwards NC, et al: Subclinical abnormalities of left ventricular myocardial deformation in early-stage chronic kidney disease: the precursor of uremic cardiomyopathy? J Am Soc Echocardiogr 2008;21:1293–1298.
  11. Jolly SE, et al: Racial and ethnic differences in mortality among individuals with chronic kidney disease: results from the Kidney Early Evaluation Program (KEEP). Clin J Am Soc Nephrol 2011;6:1858–1865.


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