Table of Contents
To view the fulltext, log-in or choose pay-per-view options:
Get Access

EMDR Therapy Modulates the Default Mode Network in a Subsyndromal, Traumatized Bipolar Patient

Landin-Romero R.a, b · Novo P.a, c · Vicens V.a, b · McKenna P.J.a, b · Santed A.d · Pomarol-Clotet E.a, b · Salgado-Pineda P.a, b · Shapiro F.e · Amann B.L.a, b
aFIDMAG Research Foundation Germanes Hospitalàries, bCIBERSAM, cDepartament de Psiquiatria i Medicina Legal, Doctorat de Psiquiatria i Psicología Clínica, Universitat Autònoma de Barcelona, dCentro Adala de Atencion Psicologica, Barcelona, Spain; eMental Research Institute, Palo Alto, Calif., USA Neuropsychobiology 2013;67:181-184 (DOI:10.1159/000346654)

Abstract

Background: Some functional imaging abnormalities found in bipolar disorder are state related, whereas others persist into euthymia. It is uncertain to what extent these latter changes may reflect continuing subsyndromal affective fluctuations and whether those can be modulated by therapeutic interventions. Method: We report functional magnetic resonance imaging (fMRI) findings during performance of the n-back working memory task in a bipolar patient who showed a marked improvement in subsyndromal affective symptoms after receiving eye movement desensitization and reprocessing (EMDR) therapy in the context of a clinical trial. Results: The patient's clinical improvement was accompanied by marked changes in functional imaging, as compared to 30 healthy subjects. fMRI changes were noted particularly in deactivation, with failure of deactivation in the medial frontal cortex partially normalizing after treatment. Conclusions: This case supports the potential therapeutic overall benefit of EMDR in traumatized bipolar patients and suggests a possible neurobiological mechanism of action: normalization of default mode network dysfunction.

 

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.


Pay-per-View Options
Direct payment This item at the regular price: USD 33.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 23.00