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Vol. 79, No. 3, 2013
Issue release date: April 2013
Section title: Novel Insights from Clinical Practice
Horm Res Paediatr 2013;79:185-188
(DOI:10.1159/000346903)

Bartonella henselae Infection Associated with Autoimmune Thyroiditis in a Child

Chiuri R.M. · Matronola M.F. · Di Giulio C. · Comegna L. · Chiarelli F. · Blasetti A.
Department of Pediatrics, University of Chieti, Chieti, Italy

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Article / Publication Details

First-Page Preview
Abstract of Novel Insights from Clinical Practice

Received: 9/27/2012 3:53:02 PM
Accepted: 1/4/2013
Published online: 2/22/2013

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 1

ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)

For additional information: http://www.karger.com/HRP

Abstract

Background: Bartonella henselae was discovered a quarter of a century ago as the causative agent of cat-scratch disease. More recently, Bartonella has been found to be responsible for a broad range of clinical syndromes (prolonged fever, hepatosplenic disease, encephalopathies, ocular disease) and associated with autoimmune conditions. Case: This is the first report of autoimmune thyroiditis related to B. henselae infection. We describe an 11-year-old boy who presented with goiter and weight loss. At the time of admission a 2 × 1 cm mildly tender right supraclavicular lymph node was noted in association with an erythematous papule at the same side of the neck. We describe an association of autoimmune hyperthyroidism (Hashitoxicosis) with B. henselae infection (cat-scratch disease) in a pediatric patient. Conclusion: Different types of infections are implicated in the pathogenesis of autoimmune thyroid disease through molecular mimicry or other mechanisms, despite their role is disputed. We speculated that autoimmune thyroiditis should be added to the spectrum of clinical syndromes that can be triggered by B. henselae.


Article / Publication Details

First-Page Preview
Abstract of Novel Insights from Clinical Practice

Received: 9/27/2012 3:53:02 PM
Accepted: 1/4/2013
Published online: 2/22/2013

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 1

ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)

For additional information: http://www.karger.com/HRP


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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