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Vol. 82, No. 6, 2013
Issue release date: October 2013
Psychother Psychosom 2013;82:401-403
(DOI:10.1159/000353174)

Can Assessors in a Psychotherapy Trial Be Successfully Blinded? Analysis of a Randomized Controlled Trial on Psychotherapy for Refractory Insomnia in Residual Depression

Watanabe N. · Furukawa T.A. · Shimodera S. · Katsuki F. · Fujita H. · Sasaki M. · Suga Y. · Kakeda K. · Perlis M.L.
aDepartment of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Tokyo, bDepartment of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, cDepartments of Health Promotion and Human Behavior and Clinical Epidemiology, Kyoto University Graduate School of Medicine/School of Public Health, Kyoto, dDepartment of Neuropsychiatry, Kochi Medical School, Kochi University, Kochi, eDepartment of Psychiatric and Mental Health Nursing, Nagoya City University School of Nursing, Nagoya, and fHealth Care Center, Japan Advanced Institute of Science and Technology, Kanazawa, Japan; gBehavioral Sleep Medicine Program, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pa., USA

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Abstract of Letter to the Editor

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References

  1. Baethge C, Assall OP, Baldessarini RJ: Systematic review of blinding assessment in randomized controlled trials in schizophrenia and affective disorders 2000-2010. Psychother Psychosom 2013;82:152-160.
  2. Boutron I, Guittet L, Estellat C, Moher D, Hrobjartsson A, Ravaud P: Reporting methods of blinding in randomized trials assessing nonpharmacological treatments. PLoS Med 2007;4:e61.
  3. Manber R, Edinger JD, Gress JL, San Pedro-Salcedo MG, Kuo TF, Kalista T: Cognitive behavioral therapy for insomnia enhances depression outcome in patients with comorbid major depressive disorder and insomnia. Sleep 2008;31:489-495.
  4. Watanabe N, Furukawa TA, Shimodera S, Morokuma I, Katsuki F, Fujita H, Sasaki M, Kawamura C, Perlis ML: Brief behavioral therapy for refractory insomnia in residual depression: an assessor-blind, randomized controlled trial. J Clin Psychiatry 2011;72:1651-1658.
  5. Furukawa TA, Akechi T, Azuma H, Okuyama T, Higuchi T: Evidence-based guidelines for interpretation of the Hamilton Rating Scale for Depression (HAM-D). J Clin Psychopharmacol 2007;27:531-534.
  6. Morin CM, Vallieres A, Guay B, Ivers H, Savard J, Merette C, Bastien C, Baillargeon L: Cognitive behavioral therapy, singly and combined with medication, for persistent insomnia: a randomized controlled trial. JAMA 2009;301:2005-2015.
  7. Perlis RH, Ostacher M, Fava M, Nierenberg AA, Sachs GS, Rosenbaum JF: Assuring that double-blind is blind. Am J Psychiatry 2010;167:250-252.
  8. Basoglu M, Marks I, Livanou M, Swinson R: Double-blindness procedures, rater blindness, and ratings of outcome. Observations from a controlled trial. Arch Gen Psychiatry 1997;54:744-748.
  9. Boutron I, Estellat C, Ravaud P: A review of blinding in randomized controlled trials found results inconsistent and questionable. J Clin Epidemiol 2005;58:1220-1226.


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