Journal Mobile Options
Table of Contents
Vol. 163, No. 1, 2014
Issue release date: January 2014
Section title: Original Paper
Int Arch Allergy Immunol 2014;163:36-42
(DOI:10.1159/000356336)

A Computerized Asthma-Specific Quality of Life: A Novel Tool for Reflecting Asthma Control and Predicting Exacerbation

Kim M.-A. · Ye Y.-M. · Park J.-W. · Lee J.-H. · Lee S.-K. · Kim C.-W. · Jung K.-S. · Kim J.-H. · Yoo H.-S. · Kim S.-H. · Shin Y.S. · Nahm D.-H. · Park H.-S. · on behalf of the Premier Researchers Aiming New Era in Asthma and Allergic Diseases (PRANA) Study Group
aDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, bDepartment of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, cDepartment of Internal Medicine, Dong-A University College of Medicine, Busan, dDepartment of Internal Medicine, Inha University College of Medicine, Incheon, eDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University Medical School, Pyeongchon, Republic of Korea

Do you have an account?

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

Register and profit from personalized services (MyKarger) Login Information

Please create your User ID & Password





Contact Information









I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger (new!)
  • Unrestricted printing, no saving restrictions for personal use
  • Reduced rates with a PPV account
read more

Direct: USD 38.00
Account: USD 26.50

Select

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restriction apply

Rental: USD 8.50
Cloud: USD 20.00

Select

Subscribe

  • Automatic perpetual access to all articles of the subscribed year(s)
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 2/20/2013
Accepted: 10/7/2013
Published online: 11/16/2013

Number of Print Pages: 7
Number of Figures: 3
Number of Tables: 3

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA

Abstract

Background: Proper assessment of health-related quality of life is essential to achieve and maintain a controlled status in asthmatic patients. We developed our own computerized asthma-specific quality-of-life (cA-QOL) questionnaire based on in-depth interviews with adult asthmatic patients. In this study, we evaluated this cA-QOL in terms of the Asthma Control Test (ACT) score and Global Initiative for Asthma (GINA) guidelines as well as asthma exacerbation, and compared it with the asthma-related quality-of-life questionnaire (AQLQ). Methods: We conducted a multicenter, prospective, observational study in 133 adult asthmatic patients recruited from 5 university hospitals in South Korea, who were randomized into 2 groups according to the operating order of the cA-QOL and AQLQ. At every visit (3-month interval), physicians evaluated asthma control status with monitoring spirometry. The self-administered cA-QOL, AQLQ(S) and ACT were completed. Results: The cA-QOL scores correlated significantly with ACT and AQLQ(S) scores (r = 0.814, p < 0.001; r = 0.900, p < 0.001). The cA-QOL score was significantly lower where the ACT score was <19, in the patients with an uncontrolled asthma status according to the GINA guidelines and in those with asthma exacerbation (p < 0.001, respectively). A multivariate analysis showed that this cA-QOL was a significant parameter associated with an uncontrolled asthma status and asthma exacerbation (p < 0.001, p = 0.045, p = 0.019, respectively). Conclusion: The cA-QOL is a valid tool for reflecting current asthma control status and for assessment to predict the future risk of asthma exacerbation in adult asthmatics.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 2/20/2013
Accepted: 10/7/2013
Published online: 11/16/2013

Number of Print Pages: 7
Number of Figures: 3
Number of Tables: 3

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: http://www.karger.com/IAA


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Global Initiative for Asthma (GINA) 2012: From the global strategy for asthma management and prevention. http://www.Ginasthma.Org/
  2. Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR: Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999;14:902-907.
  3. Vollmer WM, Markson LE, O'Connor E, Sanocki LL, Fitterman L, Berger M, Buist AS: Association of asthma control with health care utilization and quality of life. Am J Respir Crit Care Med 1999;160:1647-1652.
  4. Chen H, Gould MK, Blanc PD, Miller DP, Kamath TV, Lee JH, Sullivan SD: Asthma control, severity, and quality of life: quantifying the effect of uncontrolled disease. J Allergy Clin Immunol 2007;120:396-402.
  5. McTaggart-Cowan HM, Marra CA, Yang Y, Brazier JE, Kopec JA, FitzGerald JM, Anis AH, Lynd LD: The validity of generic and condition-specific preference-based instruments: the ability to discriminate asthma control status. Qual Life Res 2008;17:453-462.
  6. Hwang E-K, Jin HJ, Nam Y-H, Shin YS, Ye Y-M, Nahm D-H, Park H-S: The predictors of poorly controlled asthma in elderly. Allergy Asthma Immunol Res 2012;4:270.
  7. Baiardini I, Bousquet PJ, Brzoza Z, Canonica GW, Compalati E, Fiocchi A, Fokkens W, van Wijk RG, La Grutta S, Lombardi C, Maurer M, Pinto AM, Ridolo E, Senna GE, Terreehorst I, Bom AT, Bousquet J, Zuberbier T, Braido F, Global Allergy and Asthma European Network: Recommendations for assessing patient-reported outcomes and health-related quality of life in clinical trials on allergy: A GA(2)LEN taskforce position paper. Allergy 2010;65:290-295.
  8. Juniper EF, Guyatt GH, Epstein RS, Ferrie PJ, Jaeschke R, Hiller TK: Evaluation of impairment of health related quality of life in asthma: development of a questionnaire for use in clinical trials. Thorax 1992;47:76-83.
  9. Juniper EF, Buist AS, Cox FM, Ferrie PJ, King DR: Validation of a standardized version of the asthma quality of life questionnaire. Chest 1999;115:1265-1270.
  10. Kwon H-S, Lee S-H, Yang M-S, Lee S-M, Kim S-H, Kim D-I, Sohn S-W, Park C-H, Park H-W, Kim S-S, Cho S-H, Min K-U, Kim Y-Y, Chang Y-S: Correlation between the Korean version of asthma control test and health-related quality of life in adult asthmatics. J Korean Med Sci 2008;23:621.
  11. Park J-W, Cho Y-S, Lee S-Y, Nahm D-H, Kim Y-K, Kim D-K, Sohn J-W, Park J-K, Jee Y-K, Cho Y-J, Yoon H-J, Kim M-K, Park H-S, Choi B-W, Choi I-S, Park C-K, Min K-U, Moon H-B, Park S-H, Lee Y-K, Kim N-S, Hong C-S: Multi-center study for the utilization of quality of life questionnaire for adult Korean asthmatics (QLQAKA). J Asthma Allergy Clin Immunol 2000;20:467-479.
  12. Lee EH, Kim SH, Choi JH, Jee YK, Nahm DH, Park HS: Development and evaluation of an asthma-specific quality of life (A-QOL) questionnaire. J Asthma 2009;46:716-721.
  13. Marks GB, Dunn SM, Woolcock AJ: A scale for the measurement of quality of life in adults with asthma. J Clin Epidemiol 1992;45:461-472.
  14. Lee EH: Computerized measurement for asthma-specific quality of life: comparison with a conventional paper-and-pencil questionnaire. J Korean Acad Nurs 2009;39:781-787.
  15. Oh EG, Kim SH, Kim BH, Park MS, Kim SK, Kim YS: Health behaviour and quality of life in Korean adults with respiratory disease: National Health Survey, 2005. Int J Tuberc Lung Dis 2010;14:772-778.
  16. Sims EJ, Price D, Haughney J, Ryan D, Thomas M: Current control and future risk in asthma management. Allergy Asthma Immunol Res 2011;3:217.
  17. Siroux V, Boudier A, Bousquet J, Vignoud L, Gormand F, Just J, Le Moual N, Leynaert B, Nadif R, Pison C, Scheinmann P, Vervloet D, Anto JM, Kauffmann F, Pin I: Asthma control assessed in the EGEA epidemiological survey and health-related quality of life. Respir Med 2012;106:820-828.
  18. Benito-Fernandez J, Mojica-Munoz E, Andres-Olaizola A, Gonzalez-Balenciaga M, Urrutia-Adan M, Martinez-Indart L, Mintegi S: Impact on quality of life by improving asthma control medication in patients with persistent asthma in a paediatric emergency department. Eur J Emerg Med 2013;20:350-355.
  19. Purokivi M, Koskela H, Kontra K: Determinants of asthma control and quality of life in stable asthma: evaluation of two new cough provocation tests. Clin Respir J 2013;7:253-260.
  20. Maio S, Baldacci S, Simoni M, Angino A, Martini F, Cerrai S, Sarno G, Pala A, Bresciani M, Paggiaro P, Viegi G: Impact of asthma and comorbid allergic rhinitis on quality of life and control in patients of Italian general practitioners. J Asthma 2012;49:854-861.