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Table of Contents
Vol. 228, No. 3, 2014
Issue release date: June 2014
Section title: Case and Review
Dermatology 2014;228:193-197
(DOI:10.1159/000357729)

Sight-Threatening Ocular Manifestations of Acute Febrile Neutrophilic Dermatosis (Sweet's Syndrome)

Baartman B. · Kosari P. · Warren C.C. · Ali S. · Jorizzo J.L. · Sato M. · Kurup S.K.
aDepartment of Ophthalmology, Wake Forest University Eye Center, and Departments of bDermatology and cPathology, Wake Forest University Baptist Medical Center, Winston-Salem, N.C., USA; dDepartment of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan

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Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 3/4/2013 6:32:01 AM
Accepted: 12/2/2013
Published online: 3/1/2014

Number of Print Pages: 5
Number of Figures: 6
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM

Abstract

Sweet's syndrome is a primarily dermatologic disorder with many features of systemic inflammation. It is generally characterized by a neutrophilic dermatosis in the setting of fever and an elevated white blood cell count. Inflammation has been described to occur in many organ systems including the lung, bone, liver, spleen, brain and eye. Ocular inflammation is a well-known comorbidity that may occur in the setting of Sweet's syndrome, including conjunctivitis, episcleritis, scleritis, iritis and choroiditis, among other forms. In the current article, we have compiled a series of cases that describe three separate patients who demonstrated a rare form of ocular involvement in Sweet's syndrome, retinal vasculitis. The evidence from these three cases and other reports in recent ophthalmologic literature suggest overlapping of ocular manifestations of Sweet's syndrome and the closely related Behçet's disease. It is important to be aware of the sometimes challenging differential between these two disorders and their sight-threatening complications.


Article / Publication Details

First-Page Preview
Abstract of Case and Review

Received: 3/4/2013 6:32:01 AM
Accepted: 12/2/2013
Published online: 3/1/2014

Number of Print Pages: 5
Number of Figures: 6
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: http://www.karger.com/DRM


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

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    External Resources

  9. Bonamigo RR, Razera F, Olm GS: Neutrophilic dermatoses: part I. An Bras Dermatol 2011;86:11-25; quiz 26-27.
  10. Hassikou H, Tabache F, Baaj M, Safi S, Hadri L: Sweet's syndrome in Behcet's disease. Joint Bone Spine 2007;74:495-496.
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    External Resources

  12. Walton RC, Ashmore ED: Retinal vasculitis. Curr Opin Ophthalmol 2003;14:413-419.
  13. Howe LJ, Stanford MR, Edelsten C, Graham EM: The efficacy of systemic corticosteroids in sight-threatening retinal vasculitis. Eye (Lond) 1994;8:443-447.