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Nutritional Care of Preterm Infants

Scientific Basis and Practical Guidelines

Editor(s): Koletzko B. (Munich) 
Poindexter B. (Indianapolis, Ind.) 
Uauy R. (Santiago de Chile) 
Table of Contents
Vol. 110, 2014
Section title:  
Koletzko B, Poindexter B, Uauy R (eds): Nutritional Care of Preterm Infants: Scientific Basis and Practical Guidelines. World Rev Nutr Diet. Basel, Karger, 2014, vol 110, pp 99-120
(DOI:10.1159/000358461)

Water, Sodium, Potassium and Chloride

Fusch C. · Jochum F.
aDepartment of Pediatrics, McMaster University & Hamilton Health Sciences, Hamilton, Ont., Canada; bDepartment of Pediatrics, Evangelisches Waldkrankenhaus Spandau, Berlin, Germany

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Article / Publication Details

First-Page Preview
Abstract of  

Published online: 4/11/2014
Cover Date: 2014

Number of Print Pages: 22
Number of Figures: 3
Number of Tables: 0

ISBN: 978-3-318-02640-5 (Print)
eISBN: 978-3-318-02641-2 (Online)

Abstract

The sudden disruption of excessive placental supply with fluids and electrolytes is challenging for neonatal physiology during the period of postnatal adaptation. Different from many other nutrients, the body experiences large changes in daily requirements during the first 7-14 postnatal days, and on the other hand does not tolerate conditions of excess and deficiency very well. Imbalances of fluid and electrolytes are common in neonates, which - in addition - might be further aggravated by NICU treatment procedures. Therefore, fluid and electrolyte management can be one of the most challenging aspects of neonatal care of the premature infant. An understanding of the physiological adaptation process to extrauterine life - and how immaturity effects that transition - is the basis which is needed to understand and manage fluid and electrolyte balance in premature infants. This chapter addresses the physiology of postnatal adaptation and other aspects of fluid and electrolyte management (concerning potassium, sodium and chloride) of the preterm infant.


Article / Publication Details

First-Page Preview
Abstract of  

Published online: 4/11/2014
Cover Date: 2014

Number of Print Pages: 22
Number of Figures: 3
Number of Tables: 0

ISBN: 978-3-318-02640-5 (Print)
eISBN: 978-3-318-02641-2 (Online)


Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Friis-Hansen B: Water - the major nutrient. Acta Paediatr Scand Suppl 1982;299:11-16.
  2. Friis-Hansen B: Body water compartments in children: changes during growth and related changes in body composition. Pediatrics 1961;28:169-174.

    External Resources

  3. Fomon SJ, Haschke F, Ziegler EE, Nemeth M: Body composition of reference children from birth to age 10 years. Am J Clin Nutr 1982;35:1169-1175.

    External Resources

  4. Widdowson E: Changes of body composition during growth; in Davis J, Dobbing J (eds): Scientific Foundations of Paediatrics. London, Heinemann, 1981, pp 330-342.
  5. Fusch C, Slotboom J, Fuehrer U, Schumacher R, Keisker A, Zimmermann W, Moessinger AC, Boesch C, Blum J: Neonatal body composition: dual-energy X-ray absorptiometry, magnetic resonance imaging, and three-dimensional chemical shift imaging versus chemical analysis in piglets. Pediatr Res 1999;46:465-473.
  6. Nicholson J, Pesce M: Laboratory testing and reference values in infants and children; in Nelson W, Behrman R, Kliegman R, Arvin A (eds): Textbook of Pediatrics, ed 15. Philadelphia, Saunders, 2002, pp 2031-2084.
  7. Raubenstine DA, Ballantine TV, Greecher CP, Webb SL: Neonatal serum protein levels as indicators of nutritional status: normal values and correlation with anthropometric data. J Pediatr Gastroenterol Nutr 1990;10:53-61.
  8. Roithmaier A, Arlettaz R, Bauer K, Bucher HU, Krieger M, Duc G, Versmold HT: Randomized controlled trial of Ringer solution versus serum for partial exchange transfusion in neonatal polycythaemia. Eur J Pediatr 1995;154:53-56.
  9. Offringa PJ, Boersma ER, Brunsting JR, Meeuwsen WP, Velvis H: Weight loss in full-term Negroid infants: relationship to body water compartments at birth? Early Hum Dev 1990;21:73-81.
  10. Shaffer SG, Ekblad H, Brans YW: Estimation of extracellular fluid volume by bromide dilution in infants less than 1,000 grams birth weight. Early Hum Dev 1991;27:19-24.
  11. Andersson B: Regulation of body fluids. Annu Rev Physiol 1977;39:185-200.
  12. Boehles H: Ernährungsstörungen im Kindesalter. Stuttgart, Wissenschaftliche Verlagsgesellschaft, 1991, p 26.
  13. Robertson G, Berl T: Water metabolism; in Brenner BM, Rector F (eds): The Kidney. Philadelphia, Saunders, 1986, pp 385-431.
  14. Guyton A, Scanlon L, Armstrong G: Effects of pressoreceptor reflex and Cushing reflex on urinary output. Fed Proc 1952;11:61-62.
  15. Mann JF, Johnson AK, Ganten D, Ritz E: Thirst and the renin-angiotensin system. Kidney Int Suppl 1987;21(suppl):27-34.

    External Resources

  16. Linshaw MA: Selected aspects of cell volume control in renal cortical and medullary tissue. Pediatr Nephrol 1991;5:653-665.
  17. Macknight AD, Leaf A: Regulation of cellular volume. Physiol Rev 1977;57:510-573.

    External Resources

  18. Gruwel ML, Alves C, Schrader J: Na+/K+-ATPase in endothelial cell energetics: 23Na nuclear magnetic resonance and calorimetry study. Am J Physiol 1995;268:H351-H358.

    External Resources

  19. Carlton DP, Cummings JJ, Scheerer RG, Bland RD: Lung vascular protein permeability in preterm fetal and mature newborn sheep. J Appl Physiol 1994;77:782-788.

    External Resources

  20. Bhat R, Malalis L, Shukla A, Vidyasagar D: Colloid osmotic pressure in infants with hyaline membrane disease. Chest 1983;83:776-779.
  21. Ekblad H: Postnatal changes in colloid osmotic pressure in premature infants: in healthy infants, in infants with respiratory distress syndrome, and in infants born to mothers with premature rupture of membranes. Gynecol Obstet Invest 1987;24:95-100.
  22. Kero P, Korvenranta H, Alamaakala P, Selanne P, Kiilholma P, Valimaki I: Colloid osmotic pressure of cord blood in relation to neonatal outcome and mode of delivery. Acta Paediatr Scand Suppl 1983;305:88-91.
  23. Sola A, Gregory GA: Colloid osmotic pressure of normal newborns and premature infants. Crit Care Med 1981;9:568-572.

    External Resources

  24. Wu PY, Udani V, Chan L, Miller FC, Henneman CE: Colloid osmotic pressure: variations in normal pregnancy. J Perinat Med 1983;11:193-199.
  25. Jobe A, Jacobs H, Ikegami M, Berry D: Lung protein leaks in ventilated lambs: effects of gestational age. J Appl Physiol 1985;58:1246-1251.

    External Resources

  26. Brunette MG, Leclerc M, Claveau D: Na+ transport by human placental brush border membranes: are there several mechanisms? J Cell Physiol 1996;167:72-80.
  27. Smith CH, Moe AJ, Ganapathy V: Nutrient transport pathways across the epithelium of the placenta. Annu Rev Nutr 1992;12:183-206.
  28. Spitzer A: Renal physiology and function development; in Edelmann CM (ed): The Kidney and Urinary Tract. Boston, Little Brown, 1978, pp 25-128.
  29. Modi N: Development of renal function. Br Med Bull 1988;44:935-956.

    External Resources

  30. Haycock GB: Development of glomerular filtration and tubular sodium reabsorption in the human fetus and newborn. Br J Urol 1998;81(suppl 2):33-38.
  31. Martin D: Wasser und anorganische Elemente; in Harpner H, Martin D, Mayes P, Rodwell V (eds): Medizinische Biochemie, ed 19. Berlin, Springer, 1983, pp 657-671.

    External Resources

  32. Kurzner SI, Garg M, Bautista DB, Sargent CW, Bowman CM, Keens TG: Growth failure in bronchopulmonary dysplasia: elevated metabolic rates and pulmonary mechanics. J Pediatr 1988;112:73-80.
  33. Weinstein MR, Oh W: Oxygen consumption in infants with bronchopulmonary dysplasia. J Pediatr 1981;99:958-961.
  34. Baumgart S: Radiant energy and insensible water loss in the premature newborn infant nursed under a radiant warmer. Clin Perinatol 1982;9:483-503.

    External Resources

  35. Baumgart S: Partitioning of heat losses and gains in premature newborn infants under radiant warmers. Pediatrics 1985;75:89-99.

    External Resources

  36. Wheldon AE, Rutter N: The heat balance of small babies nursed in incubators and under radiant warmers. Early Hum Dev 1982;6:131-143.
  37. Baumgart S, Engle WD, Fox WW, Polin RA: Radiant warmer power and body size as determinants of insensible water loss in the critically ill neonate. Pediatr Res 1981;15:1495-1499.
  38. Brück K: Neonatal thermal regulation; in Polin RA, Fox WW (eds): Fetal and Neonatal Physiology. Philadelphia, Saunders, 1992, pp 488-514.
  39. Hammarlund K, Sedin G, Stromberg B: Transepidermal water loss in newborn infants. VIII. Relation to gestational age and post-natal age in appropriate and small for gestational age infants. Acta Paediatr Scand 1983;72:721-728.
  40. Hey EN, Katz G: Evaporative water loss in the new-born baby. J Physiol 1969;200:605-619.

    External Resources

  41. Sedin G, Hammarlund K, Nilsson GE, Stromberg B, Oberg PA: Measurements of transepidermal water loss in newborn infants. Clin Perinatol 1985;12:79-99.

    External Resources

  42. Williams PR, Oh W: Effects of radiant warmer on insensible water loss in newborn infants. Am J Dis Child 1974;128:511-514.
  43. Wu PY, Hodgman JE: Insensible water loss in preterm infants: changes with postnatal development and non-ionizing radiant energy. Pediatrics 1974;54:704-712.

    External Resources

  44. Brück K: Heat production and temperature regulation; in Stave U (ed): Perinatal Physiology. New York, Plenum Medical, 1987, p 455.

    External Resources

  45. Sulyok E, Jequier E, Prod'hom LS: Respiratory contribution to the thermal balance of the newborn infant under various ambient conditions. Pediatrics 1973;51:641-650.
  46. Sinclair JC: Metabolic rate and temperature control; in Smith CA, Nelson N (eds): The Physiology of the Newborn Infant, ed 4. Springfield, Thomas, 1976, pp 354-415.
  47. Ziegler EE, Fomon SJ: Fluid intake, renal solute load, and water balance in infancy. J Pediatr 1971;78:561-568.
  48. Chevalier RL: Developmental renal physiology of the low birth weight pre-term newborn. J Urol 1996;156:714-719.
  49. Rees L, Brook CG, Shaw JC, Forsling ML: Hyponatraemia in the first week of life in preterm infants. Part I. Arginine vasopressin secretion. Arch Dis Child 1984;59:414-422.
  50. Svenningsen NW, Aronson AS: Postnatal development of renal concentration capacity as estimated by DDAVP test in normal and asphyxiated neonates. Biol Neonate 1974;25:230-241.
  51. Leake RD, Zakauddin S, Trygstad CW, Fu P, Oh W: The effects of large volume intravenous fluid infusion on neonatal renal function. J Pediatr 1976;89:968-972.
  52. Jhaveri MK, Kumar SP: Passage of the first stool in very low birth weight infants. Pediatrics 1987;79:1005-1007.

    External Resources

  53. Al-Dahhan J, Haycock GB, Chantler C, Stimmler L: Sodium homeostasis in term and preterm neonates. I. Renal aspects. Arch Dis Child 1983;58:335-342.
  54. Rees L, Shaw JC, Brook CG, Forsling ML: Hyponatraemia in the first week of life in preterm infants. Part II. Sodium and water balance. Arch Dis Child 1984;59:423-429.
  55. Reiter PD, Makhlouf R, Stiles AD: Comparison of 6-hour infusion versus bolus furosemide in premature infants. Pharmacotherapy 1998;18:63-68.

    External Resources

  56. Al-Dahhan J, Haycock GB, Chantler C, Stimmler L: Sodium homeostasis in term and preterm neonates. II. Gastrointestinal aspects. Arch Dis Child 1983;58:343-345.
  57. Bower TR, Pringle KC, Soper RT: Sodium deficit causing decreased weight gain and metabolic acidosis in infants with ileostomy. J Pediatr Surg 1988;23:567-572.
  58. Haycock GB: The influence of sodium on growth in infancy. Pediatr Nephrol 1993;7:871-875.
  59. Leung AK, McArthur RG, McMillan DD, Ko D, Deacon JS, Parboosingh JT, Lederis KP: Circulating antidiuretic hormone during labour and in the newborn. Acta Paediatr Scand 1980;69:505-510.
  60. Modi N, Hutton JL: The influence of postnatal respiratory adaptation on sodium handling in preterm neonates. Early Hum Dev 1990;21:11-20.
  61. Bauer K, Bovermann G, Roithmaier A, Gotz M, Proiss A, Versmold HT: Body composition, nutrition, and fluid balance during the first two weeks of life in preterm neonates weighing less than 1,500 grams. J Pediatr 1991;118:615-620.
  62. Bauer K, Buschkamp S, Marcinkowski M, Kossel H, Thome U, Versmold HT: Postnatal changes of extracellular volume, atrial natriuretic factor, and diuresis in a randomized controlled trial of high-frequency oscillatory ventilation versus intermittent positive-pressure ventilation in premature infants <30 weeks' gestation. Crit Care Med 2000;28:2064-2068.
  63. Bauer K, Versmold H: Postnatal weight loss in preterm neonates less than 1,500 g is due to isotonic dehydration of the extracellular volume. Acta Paediatr Scand Suppl 1989;360:37-42.
  64. Bauer K, Versmold H, Prolss A, De-Graaf SS, Meeuwsen-Van-der-Roest WP, Zijlstra WG: Estimation of extracellular volume in preterm infants less than 1,500 g, children, and adults by sucrose dilution. Pediatr Res 1990;27:256-259.
  65. Hartnoll G, Betremieux P, Modi N: Randomised controlled trial of postnatal sodium supplementation on body composition in 25 to 30 week gestational age infants. Arch Dis Child Fetal Neonatal Ed 2000;82:F24-F28.
  66. Maclaurin JC: Changes in body water distribution during the first two weeks of life. Arch Dis Child 1966;41:286-291.
  67. Modi N: Adaptation to extrauterine life. Br J Obstet Gynaecol 1994;101:369-370.
  68. Shaffer SG, Bradt SK, Hall RT: Postnatal changes in total body water and extracellular volume in the preterm infant with respiratory distress syndrome. J Pediatr 1986;109:509-514.
  69. Shaffer SG, Meade VM: Sodium balance and extracellular volume regulation in very low birth weight infants. J Pediatr 1989;115:285-290.
  70. Lorenz JM, Kleinman LI, Ahmed G, Markarian K: Phases of fluid and electrolyte homeostasis in the extremely low birth weight infant. Pediatrics 1995;96:484-489.

    External Resources

  71. Tang W, Ridout D, Modi N: Influence of respiratory distress syndrome on body composition after preterm birth. Arch Dis Child Fetal Neonatal Ed 1997;77:F28-F31.
  72. Bland RD: Edema formation in the newborn lung. Clin Perinatol 1982;9:593-611.

    External Resources

  73. Bland RD: Edema formation in the lungs and its relationship to neonatal respiratory distress. Acta Paediatr Scand Suppl 1983;305:92-99.
  74. Brown ER, Stark A, Sosenko I, Lawson EE, Avery ME: Bronchopulmonary dysplasia: possible relationship to pulmonary edema. J Pediatr 1978;92:982-984.
  75. Ertl T, Sulyok E, Bodis J, Csaba IF: Plasma prolactin levels in full-term newborn infants with idiopathic edema: response to furosemide. Biol Neonate 1986;49:15-20.
  76. Jefferies AL, Coates G, O'Brodovich H: Pulmonary epithelial permeability in hyaline-membrane disease. N Engl J Med 1984;311:1075-1080.
  77. Cort R: Renal function in the respiratory distress syndrome. Acta Paediatr Scand 1962;51:313-323.
  78. Guignard JP, Torrado A, Mazouni SM, Gautier E: Renal function in respiratory distress syndrome. J Pediatr 1976;88:845-850.
  79. Costarino AT, Baumgart S, Norman ME, Polin RA: Renal adaptation to extrauterine life in patients with respiratory distress syndrome. Am J Dis Child 1985;139:1060-1063.
  80. Engle WD, Arant BS, Wiriyathian S, Rosenfeld CR: Diuresis and respiratory distress syndrome: physiologic mechanisms and therapeutic implications. J Pediatr 1983;102:912-917.
  81. Heaf DP, Belik J, Spitzer AR, Gewitz MH, Fox WW: Changes in pulmonary function during the diuretic phase of respiratory distress syndrome. J Pediatr 1982;101:103-107.
  82. Langman CB, Engle WD, Baumgart S, Fox WW, Polin RA: The diuretic phase of respiratory distress syndrome and its relationship to oxygenation. J Pediatr 1981;98:462-466.
  83. Bell EF: Fluid therapy; in Sinclair JC, Bracken M (eds): Effective Care of the Newborn. Oxford, Oxford University Press, 1992, pp 59-71.
  84. Bell EF, Warburton D, Stonestreet BS, Oh W: High-volume fluid intake predisposes premature infants to necrotising enterocolitis. Lancet 1979;2:90.
  85. Bell EF, Warburton D, Stonestreet BS, Oh W: Effect of fluid administration on the development of symptomatic patent ductus arteriosus and congestive heart failure in premature infants. N Engl J Med 1980;302:598-604.
  86. Haycock GB, Aperia A: Salt and the newborn kidney. Pediatr Nephrol 1991;5:65-70.
  87. Modi N: Sodium intake and preterm babies. Arch Dis Child 1993;69:87-91.
  88. Stevenson JG: Fluid administration in the association of patent ductus arteriosus complicating respiratory distress syndrome. J Pediatr 1977;90:257-261.
  89. Van Marter LJ, Allred EN, Leviton A, Pagano M, Parad R, Moore M: Antenatal glucocorticoid treatment does not reduce chronic lung disease among surviving preterm infants. J Pediatr 2001;138:198-204.
  90. Van Marter LJ, Leviton A, Allred EN, Pagano M, Kuban KC: Hydration during the first days of life and the risk of bronchopulmonary dysplasia in low birth weight infants. J Pediatr 1990;116:942-949.
  91. Lorenz JM, Kleinman LI, Kotagal UR, Reller MD: Water balance in very low-birth-weight infants: relationship to water and sodium intake and effect on outcome. J Pediatr 1982;101:423-432.
  92. Kavvadia V, Greenough A, Dimitriou G, Forsling ML: Randomized trial of two levels of fluid input in the perinatal period - effect on fluid balance, electrolyte and metabolic disturbances in ventilated VLBW infants. Acta Paediatr 2000;89:237-241.
  93. Kavvadia V, Greenough A, Dimitriou G, Hooper R: Randomised trial of fluid restriction in ventilated very low birth weight infants. Arch Dis Child Fetal Neonatal Ed 2000;83:F91-F96.
  94. Stonestreet BS, Bell EF, Warburton D, Oh W: Renal response in low-birth-weight neonates. Results of prolonged intake of two different amounts of fluid and sodium. Am J Dis Child 1983;137:215-219.
  95. Oh W, Poindexter BB, Perritt R, Lemons JA, Bauer CR, Ehrenkranz RA, Stoll BJ, Poole K, Wright LL: Association between fluid intake and weight loss during the first ten days of life and risk of bronchopulmonary dysplasia in extremely low birth weight infants. J Pediatr 2005;147:786-790.
  96. Bell EF, Acarregui MJ: Restricted versus liberal water intake for preventing morbidity and mortality in preterm infants. Cochrane Database Syst Rev 2008;1:CD000503.
  97. Aggarwal R, Deorari AK, Paul VK: Fluid and electrolyte management in term and preterm neonates. Indian J Pediatr 2001;68:1139-1142.
  98. Chow JM, Douglas D: Fluid and electrolyte management in the premature infant. Neonatal Netw 2008;27:379-386.
  99. Murat I, Humblot A, Girault L, Piana F: Neonatal fluid management. Best Pract Res Clin Anaesthesiol 2010;24:365-374.
  100. Modi N: Management of fluid balance in the very immature neonate. Arch Dis Child Fetal Neonatal Ed 2004;89:F108-F111.
  101. Oh W: Fluid and electrolyte management of very low birth weight infants. Pediatr Neonatol 2012;53:329-333.
  102. Lorenz JM: Fluid and electrolyte therapy and chronic lung disease. Curr Opin Pediatr 2004;16:152-156.
  103. Hartnoll G: Basic principles and practical steps in the management of fluid balance in the newborn. Semin Neonatol 2003;8:307-313.
  104. Costarino AT, Gruskay JA, Corcoran L, Polin RA, Baumgart S: Sodium restriction versus daily maintenance replacement in very low birth weight premature neonates: a randomized, blind therapeutic trial. J Pediatr 1992;120:99-106.
  105. Al-Dahhan J, Haycock GB, Nichol B, Chantler C, Stimmler L: Sodium homeostasis in term and preterm neonates. III. Effect of salt supplementation. Arch Dis Child 1984;59:945-950.
  106. Al-Dahhan J, Jannoun L, Haycock GB: Effects of salt supplementation of newborn premature infants on neurodevelopmental outcome at 10-13 years of age. Arch Dis Child Fetal Neonatal Ed 2002;86:F120-F123.
  107. Hartnoll G, Betremieux P, Modi N: Randomised controlled trial of postnatal sodium supplementation in infants of 25-30 weeks gestational age: effects on cardiopulmonary adaptation. Arch Dis Child Fetal Neonatal Ed 2001;85:F29-F32.
  108. Brion LP, Soll RF: Diuretics for respiratory distress syndrome in preterm infants. Cochrane Database Syst Rev 2000;2:CD001454.
  109. Marks KH, Berman W, Friedman Z, Whiteman V, Lee C, Maisels MJ: Furosemide in hyaline membrane disease. Pediatrics 1978;62:785-788.

    External Resources

  110. Savage MD, Wilkinson AR, Baum JD, Roberton NRC: Furosemide in respiratory distress syndrome. Arch Dis Child 1975;50:709-713.
  111. Yeh TF, Shibli A, Leu ST, Ravel D, Pildes RD: Early furosemide therapy in premature infants (2,000 g) with respiratory distress syndrome: a randomised controlled trial. J Pediatr 1984;105:603-609.
  112. Salmon JB, Mythen MG: Pharmacology and physiology of colloids. Blood Rev 1993;7:114-120.
  113. Coulthard MG, Hey EN: Effect of varying water intake on renal function in healthy preterm babies. Arch Dis Child 1985;60:614-620.
  114. Tammela OK, Koivisto ME: Fluid restriction for preventing bronchopulmonary dysplasia? Reduced fluid intake during the first weeks of life improves the outcome of low-birth-weight infants. Acta Paediatr 1992;81:207-212.
  115. Ziegler EE, Fomon SJ: Major minerals; in Fomon SJ (ed): Infant Nutrition, ed 2. Philadelphia, Saunders, 1974, pp 267-297.
  116. Leslie GI, Carman G, Arnold JD: Early neonatal hyperkalaemia in the extremely premature newborn infant. J Paediatr Child Health 1990;26:58-61.
  117. Engle WD, Arant BS: Urinary potassium excretion in the critically ill neonate. Pediatrics 1984;74:259-264.

    External Resources

  118. Nakamaru M, Misono KS, Naruse M, Workman RJ, Inagami T: A role for the adrenal renin-angiotensin system in the regulation of potassium-stimulated aldosterone production. Endocrinology 1985;117:1772-1778.
  119. Arant BS, Seikaly MG: Intrarenal angiotensin II may regulate developmental changes in renal blood flow. Pediatr Nephrol 1989;3:C142.
  120. Butterfield J, Lubchenco L, Bergstedt J, O'Brien D: Patterns in electrolyte and nitrogen balance in the newborn premature infant. Pediatrics 1960;26:777-791.

    External Resources

  121. Gross SJ: Growth and biochemical response of preterm infants fed human milk or modified infant formula. N Engl J Med 1983;308:237-241.
  122. Engelke SC, Shah BL, Vasan U, Raye JR: Sodium balance in very low-birth-weight infants. J Pediatr 1978;93:837-841.
  123. Babson SG, Bramhall JL: Diet and growth in the premature infant. The effect of different dietary intakes of ash-electrolyte and protein on weight gain and linear growth. J Pediatr 1969;74:890-900.
  124. Raiha NC, Heinonen K, Rassin DK, Gaull GE: Milk protein quantity and quality in low-birth-weight infants. I. Metabolic responses and effects on growth. Pediatrics 1976;57:659-684.

    External Resources

  125. Polberger SK, Axelsson IA, Raiha NC: Growth of very low birth weight infants on varying amounts of human milk protein. Pediatr Res 1989;25:414-419.
  126. Day GM, Radde IC, Balfe JW, Chance GW: Electrolyte abnormalities in very low birth weight infants. Pediatr Res 1976;10:522-526.
  127. Asano H, Taki M, Igarashi Y: Sodium homeostasis in premature infants during the early postnatal period: results of relative low volume of fluid and sodium intake (abstract). Pediatr Nephrol 1987;1:C38.
  128. Ekblad H, Kero P, Takala J, Korvenranta H, Valimaki I: Water, sodium and acid-base balance in premature infants: therapeutical aspects. Acta Paediatr Scand 1987;76:47-53.
  129. Kojima T, Fukuda Y, Hirata Y, Matsuzaki S, Kobayashi Y: Effects of aldosterone and atrial natriuretic peptide on water and electrolyte homeostasis of sick neonates. Pediatr Res 1989;25:591-594.
  130. Brown ER, Stark A, Sosenko I, Lawson EE, Avery ME: Bronchopulmonary dysplasia: possible relationship to pulmonary edema. J Pediatr 1978;92:982-984.
  131. Tammela OK: Appropriate fluid regimens to prevent bronchopulmonary dysplasia. Eur J Pediatr 1995;154:S15-S18.
  132. Puangco MA, Schanler RJ: Clinical experience in enteral nutrition support for premature infants with bronchopulmonary dysplasia. J Perinatol 2000;20:87-91.
  133. Brion LP, Primhak RA: Intravenous or enteral loop diuretics for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev 2000;4:CD001453.
  134. Brion LP, Primhak RA, Yong W: Aerosolized diuretics for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev 2000;2:CD001694.
  135. Brion LP, Yong SC, Perez IA, Primhak R: Diuretics and chronic lung disease of prematurity. J Perinatol 2001;21:269-271.
  136. Stewart A, Brion LP, Ambrosio-Perez I: Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease. Cochrane Database Syst Rev 2011;9:CD001817.
  137. Hoffman DJ, Gerdes JS, Abbasi S: Pulmonary function and electrolyte balance following spironolactone treatment in preterm infants with chronic lung disease: a double-blind, placebo-controlled, randomized trial. J Perinatol 2000;20:41-45.
  138. Cummings JJ, D'Eugenio DB, Gross SJ: A controlled trial of dexamethasone in preterm infants at high risk for bronchopulmonary dysplasia. N Engl J Med 1989;320:1505-1510.
  139. Durand M, Sardesai S, McEvoy C: Effects of early dexamethasone therapy on pulmonary mechanics and chronic lung disease in very low birth weight infants: a randomized, controlled trial. Pediatrics 1995;95:584-590.

    External Resources

  140. Kari MA, Heinonen K, Ikonen RS, Koivisto M, Raivio KO: Dexamethasone treatment in preterm infants at risk for bronchopulmonary dysplasia. Arch Dis Child 1993;68:566-569.
  141. Merritt TA, Hallman M, Berry C, Pohjavuori M, Edwards DK, Jaaskelainen J, Grafe MR, Vaucher Y, Wozniak P, Heldt G, et al: Randomized, placebo- controlled trial of human surfactant given at birth versus rescue administration in very low birth weight infants with lung immaturity. J Pediatr 1991;118:581-594.
  142. Brem AS: Insights into glucocorticoid-associated hypertension. Am J Kidney Dis 2001;37:1-10.
  143. Bos AF, van-Asselt WA, Okken A: Dexamethasone treatment and fluid balance in preterm infants at risk for chronic lung disease. Acta Paediatr 2000;89:562-565.
  144. Gladstone IM, Ehrenkranz RA, Jacobs HC: Pulmonary function tests and fluid balance in neonates with chronic lung disease during dexamethasone treatment. Pediatrics 1989;84:1072-1076.

    External Resources

  145. Mazkereth R, Laufer J, Jordan S, Pomerance JJ, Boichis H, Reichman B: Effects of theophylline on renal function in premature infants. Am J Perinatol 1997;14:45-49.
  146. Aszterbaum M, Feingold KR, Menon GK, Williams ML: Glucocorticoids accelerate fetal maturation of the epidermal permeability barrier in the rat. J Clin Invest 1993;91:2703-2708.
  147. Okah FA, Pickens WL, Hoath SB: Effect of prenatal steroids on skin surface hydrophobicity in the premature rat. Pediatr Res 1995;37:402-408.
  148. Omar SA, DeCristofaro JD, Agarwal BI, La-Gamma EF: Effects of prenatal steroids on water and sodium homeostasis in extremely low birth weight neonates. Pediatrics 1999;104:482-488.

    External Resources

  149. Smith LM, Ervin MG, Wada N, Ikegami M, Polk DH, Jobe AH: Antenatal glucocorticoids alter postnatal preterm lamb renal and cardiovascular responses to intravascular volume expansion. Pediatr Res 2000;47:622-627.
  150. Berry LM, Polk DH, Ikegami M, Jobe AH, Padbury JF, Ervin MG: Preterm newborn lamb renal and cardiovascular responses after fetal or maternal antenatal betamethasone. Am J Physiol 1997;272:R1972-R1979.

    External Resources

  151. Ervin MG, Berry LM, Ikegami M, Jobe AH, Padbury JF, Polk DH: Single dose fetal betamethasone administration stabilizes postnatal glomerular filtration rate and alters endocrine function in premature lambs. Pediatr Res 1996;40:645-651.
  152. Ervin MG, Seidner SR, Leland MM, Ikegami M, Jobe AH: Direct fetal glucocorticoid treatment alters postnatal adaptation in premature newborn baboons. Am J Physiol 1998;274:R1169-R1176.

    External Resources

  153. Lorenz JM: Assessing fluid and electrolyte status in the newborn. National Academy of Clinical Biochemistry. Clin Chem 1997;43:205-210.

    External Resources

  154. Fusch C, Jochum F: Water, sodium, potassium and chloride; in Tsang RC, Uauy R, Koletzko B, Zlotkin S (eds): Nutrition of the Preterm Infant. Cincinnati, Digital Educational Publishing, Inc, 2005, pp 201-245.