Journal Mobile Options
Table of Contents
Vol. 85, No. 1, 2000
Issue release date: May 2000

Dimensions of Arteriovenous Fistulas in Patients with Autosomal Dominant Polycystic Kidney Disease

Hadimeri H. · Hadimeri U. · Attman P.-O. · Nyberg G.
To view the fulltext, log in and/or choose pay-per-view option

Individual Users: Register with Karger Login Information

Please create your User ID & Password

Contact Information

I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in


Background/Aim: Aneurysms are known manifestations of autosomal dominant polycystic kidney disease (ADPKD). We investigated whether the dimensions of arteriovenous fistulas created for performance of haemodialysis were affected by the original disease. Methods: The lumen diameter of the fistula was studied by ultrasound in 19 patients with ADPKD and in 19 control patients. The patients’ sex, age, the duration of their fistulas, haemoglobin values and blood pressure levels were similar in both groups. The monitoring was performed along the forearm part of the vein, and the maximal diameter was measured. The diameters at the two needle insertion sites were also measured. Results: The ADPKD patients had a significantly higher fistula diameter than the control patients: 12 (range 8–19) mm versus 8 (range 6–24) mm at the widest level (p = 0.003). There were no significant differences in the diameters at the needle insertion sites. Conclusion: The receiving veins of arteriovenous fistulas in patients with ADPKD have an abnormality that causes a greater than normal dilatation in response to the arterialization. We postulate that this phenomenon is linked with the increased prevalence of aneurysms in ADPKD.

Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.


  1. Chauveau D, Pirson Y,Verellen-Dumoulin C, Macnicol A, Gonzalo A, Grünfeld J-P: Intracranial aneurysms in autosomal dominant polycystic kidney disease. Kidney Int 1994;45:1140–1146.
  2. Fick GM, Johnson AM, Hammond WS, Gabow PA: Causes of death in autosomal dominant polycystic kidney disease. J Am Soc Nephrol 1995;5:2048–2056.
  3. Gabow PA: Autosomal dominant polycystic kidney disease. N Engl J Med 1993;329:332–342.
  4. Leier CV, Baker PB, Kilman JW, Wooley CF: Cardiovascular abnormalities associated with adult polycystic kidney disease. Ann Intern Med 1984;100:683–688.
  5. Schievink WI, Torres VE, Wiebers DO, Houston J III: Intracranial arterial dolichoectasia in autosomal dominant polycystic kidney disease. J Am Soc Nephrol 1997;8:1298–1303.
  6. Chapman JR, Hilson AJW: Polycystic kidneys and abdominal aortic aneurysms. Lancet 1980;i:646–647.
  7. Hartman DS: Autosomal dominant polycystic kidney disease complicated by thoracic aortic dissection. AJR 1994;162:1454.
  8. Hadimeri H, Lamm C, Nyberg G: Coronary aneurysms in patients with autosomal dominant polycystic kidney disease. J Am Soc Nephrol 1998;9:837–841.
  9. Redmond HP, FitzGerald DE, Walker JF, Donohoe J: A non-invasive method in the assessment of surgically created arteriovenous fistulae for uraemia. Eur J Vasc Surg 1987;1:311–314.

    External Resources

  10. Carone FA, Bacallo R, Kanwar Y: Role of the matrix in autosomal dominant polycystic kidney disease. Ren Fail 1998;20:181–189.
  11. Geng L, Segal Y, Peissel B, Deng N, Pei Y, Carone F, Rennke HG, Glücksmann-Kuis AM, Schneider MC, Ericsson M, Reeders ST, Zhou J: Identification and localisation of polycystin, the PKD1 gene product. J Clin Invest 1996;98:2674–2682.
  12. Peters DJM, van de Wal A, Spruit L, Saris JJ, Breuning MH, Bruijn JA, de Heer E: Cellular localization and tissue distribution of polycystin-1. J Pathol 1999;188:439–446.

Pay-per-View Options
Direct payment This item at the regular price: USD 33.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 23.00