Table of Contents
To view the fulltext, log-in or choose pay-per-view options:
Get Access

Update on Tumor Cell Procoagulant Factors

Gale A.J.a · Gordon S.G.b
aDepartment of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, Calif., and bDepartment of Biology, San Diego State University, San Diego, Calif., USA Acta Haematol 2001;106:25–32 (DOI:10.1159/000046586)


Tumor cells produce tissue factor, cancer procoagulant, plasminogen activators and other factors that interact with the coagulation system, the fibrinolytic system and vascular or blood cells such that they can upset the normal homeostasis and balance between activation and inhibition of the coagulation and fibrinolytic systems. These activities play a role in tumor cell growth and metastasis, vascular wall function, and hemostasis. Proteases and their inhibitors are intimately involved in all aspects of the hemostatic, cell proliferation and cellular signalling systems. This review provides a brief examination of recent observations in this complex interaction of cellular and hemostatic factors.


Individual Users: Register with Karger Login Information

Please create your User ID & Password

Contact Information

I have read the Karger Terms and Conditions and agree.

Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50