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Vol. 31, No. 3-6, 2001
Issue release date: May–December 2001 (March 2002)
Haemostasis 2001;31:133–140

Snake Venom Proteinases as Tools in Hemostasis Studies: Structure-Function Relationship of a Plasminogen Activator Purified from Trimeresurus stejnegeri Venom

Wisner A. · Braud S. · Bon C.
Unité des Venins, Institut Pasteur, Paris, France
email Corresponding Author

 goto top of outline Key Words

  • Snake venom
  • Proteinase
  • Plasminogen activator
  • Structure-function
  • Haemostasis

 goto top of outline Abstract

Snake venom serine proteinases affect many steps of the blood coagulation cascade. Each of them usually acts selectively on one coagulation factor. They are therefore potentially useful components to study the mechanisms of action, the regulation and the structure-function relationships of human serine proteinase coagulation factors. This strategy is illustrated for a plasminogen activator purified from Trimeresurus stejnegeri venom.

Copyright © 2002 S. Karger AG, Basel

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 goto top of outline Author Contacts

Dr. Cassian Bon
Head of the Venoms Unit, Institut Pasteur
25–28, rue du Docteur-Roux
F–75724 Paris Cedex 15 (France)
Tel. +33 1 45 68 86 85, Fax +33 1 40 61 30 57, E-Mail

 goto top of outline Article Information

Number of Print Pages : 8
Number of Figures : 2, Number of Tables : 0, Number of References : 46

 goto top of outline Publication Details

Haemostasis (International Journal on Haemostasis and Thrombosis Research)
Official Journal of the ‘Mediterranean League against Thromboembolic Diseases’

Vol. 31, No. 3-6, Year 2001 (Cover Date: May-December 2001 (Released March 2002))

Journal Editor: H.C. Hemker, Maastricht; V.V. Kakkar, London
ISSN: 0301–0147 (print), 1423–0038 (Online)

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