Table of Contents
To view the fulltext, log-in or choose pay-per-view options:
Get Access

Increased Serum Levels of CD95 in Alzheimer’s Disease

Richartz E.a · Noda S.a · Schott K.a · Günthner A.a · Lewczuk P.b · Bartels M.a
aDepartment of Psychiatry and Psychotherapy, University of Tübingen, and bNeurochemistry Laboratory, University of Göttingen, Germany Dement Geriatr Cogn Disord 2002;13:178–182 (DOI:10.1159/000048650)

Abstract

There is growing evidence for a role of apoptosis in Alzheimer’s disease (AD). Recent findings suggest an increased susceptibility of lymphocytes to apoptosis in AD. To prove the hypothesis of systemic alterations in the apoptotic balance in AD, serum and cerebrospinal fluid levels of soluble CD95, which is known to mediate apoptosis, were measured. In the serum, AD patients exhibited significantly higher levels of CD95 than the controls (p = 0.017), suggesting an involvement of peripheral markers in AD.

 

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.


Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50