To view the fulltext, please log in
To view the pdf, please log in
Background/Aims: We report on a patient with lipoma of the liver associated with hepatocellular carcinoma (HCC) and polycystic liver disease. Methods: Clinical features of a patient with lipoma, HCC and polycystic liver disease are presented. A right liver lobectomy was performed. Results: Histological examination revealed a poorly differentiated multicentric HCC, as well as bile duct cysts and an encapsulated tumor of adipose tissue. The postoperative course was uncomplicated. The patient died 4 years after surgery with local recurrence of HCC. Conclusion: We find the report to be of interest because of the unusual nature of this association and the low prevalence of lipoma of the liver. The association of liver polycystic disease with other types of tumor is discussed and the literature dealing with lipomas of the liver reviewed.
Copyright / Drug Dosage
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
- Pounder DJ: Fatty tumours primary in the liver. Histopathology 1983;7:801–803.
- Gardner BP, Evans DB: Primary hepatocellular carcinoma arising in a renal transplant recipient with polycystic disease. Postgrad Med J 1983;59:120–121.
- Doty JE, Tompkins RK: Management of cystic disease of the liver; in Cady B (ed): The Surgical Clinics of North America. Liver Surgery. Philadelphia, Saunders, 1989, pp 285–295.
- Blustein PA: Association of carcinoma with congenital cystic conditions of the liver and bile ducts. Am J Gastroenterol 1977;67:40–46.
- Landais P, Grüngeld JP, Droz D et al: Cholangiocellular carcinoma in polycystic kidney and liver disease. Arch Intern Med 1984;144:2274–2276.
- Homer LW, White HJ, Read RC: Neoplastic transformation of von Meyenburg complexes of the liver. J Pathol Bacteriol 1965;96:499–502.
- Afekowna M: Lipoma of the liver: case. Medycyne 1938;848–849.
- Young S: A case of lipoma of the liver. J Pathol Bacteriol 1951;63:336–337.
- Ramchand S, Yusufuddin A, Baskerville L: Lipoma of the liver. Arch Pathol 1970;90:331–333.
- Ishak DG: Mesenchymal tumors of the liver; in Okuda K, Peters RL (eds): Hepatocellular Carcinoma. New York, Wiley, 1976, pp 247–307.
- Bruneton J, Kerboul P, Drouillard J et al: Hepatic lipomas: Ultrasound and computed tomographic findings. Gastrointest Radiol 1987;12:299–303.
- Takayasu K, Shima Y, Muramatsu Y et al: Imaging characteristics of large lipoma and angiomyolipoma of the liver. Cancer 1987;59:916–921.
- Dirschmid K, Kierler J: Lipom und Pseudolipom der Leber. Med Klin 1979;74:997–999.
- Hübener KH, Hippeli R. Das Leberlipom. Aussagewert von Sonographie, Szintigraphie, Computertomographie und Angiographie bei der Diagnostik dieses seltenen Tumors. Fortschr Röntgenstr 1980;133:176–179.
- Kampmann H, Allmendinger G. Lipome der Leber. Differentialdiagnose gegenüber Lebermetastasen mit Hilfe der Computertomographie. Z Gastroenterol 1983;21:521–525.
- Roberts JL, Fishman EK, Hartman DS et al: Lipomatous tumors of the liver: Evaluation with CT and US. Radiology 1986;158:613–617.
- Fulcheri E: Lipoma of the liver. Pathologica 1987;79:659–662.
- Itai Y, Ohtomo K, Kokubo T et al: CT and MR imaging of fatty tumors of the liver. J Comput Assist Tomogr 1987;11:253–257.
- Reading CC, Charboneau JW: Ultrasound. Hepatic lipoma. Radiographics 1990;10:511–512.
- Langsteger W, Lind P, Schneider GH et al: Lipoma of the liver: Computed tomographic, ultrasonographic and cytologic findings. Scand J Gastroenterol 1990;25:302–306.
- Martí-Bonmati L, Menor F, Vizcaino I, Vilar J: Lipoma of the liver: US, CT and MRI appearances. Gastrointestinal Radiol 1989;14:155–157.
- Sonsuz A, Ozdemis S, Akdogan M et al: Lipoma of the liver. Gastroenterology 1994;32:348–350.