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Vol. 201, No. 4, 2000
Issue release date: 2000

Homoeopathic Arnica in Postoperative Haematomas: A Double-Blind Study

Ramelet A.-A. · Buchheim G. · Lorenz P. · Imfeld M.
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Abstract

Objective: To determine whether homoeopathic Arnica can reduce postoperative haematomas in venous surgery. Design: Randomized, prospective, multicentric, double-blind placebo-controlled trial. Participants: 130 consecutive patients undergoing saphenous stripping (204 legs), hospitalized in a clinic. Interventions: A homoeopathic medicine (Arnica CH5) and an indistinguishable placebo, administered sublingually by a nurse the night before and immediately after the operation. Outcome Measures: Clinical evaluation of haematomas 6 days postoperatively. Results: Groups were well matched (sex, age, history of bleeding or thrombosis, drug intake, previous intake of homoeopathic drugs, type of operation and anaethesia, operator). One drop-out has been replaced. No statistically significant difference in postoperative haematomas was found between the Arnica and placebo groups (p = 0.342). Subanalysis of all other items did not reveal any statistical difference either. Conclusions: In this study, with this dosage, we did not observe any preventive effect of homoeopathic Arnica CH5 on poststripping haematomas.



Copyright / Drug Dosage

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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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References

  1. Linde K, Clausius N, Ramirez G, Melchart D, Eitel F, Hedges LV, Jonas WB: Are the clinical effects of homeopathy placebo effects? A meta-analysis of placebo-controlled trials. Lancet 1997;350:834–843.
  2. Baillargeon L, Drouin J, Desjardin L, Leroux D, Audet D: Les effets de l‘Arnica montana sur la coagulation sanguine. Can Fam Physician 1993;39:2362–2367.
  3. Ernst E, Pittler MH: Efficacy of homeopathic arnica. Arch Surg 1998;133:1187–1190.
  4. Vickers AJ, Fisher P, Smith C, Wyllie SE, Rees R: Homeopathic Arnica 30× is ineffective for muscle soreness after long-distance running: A randomized, double-blind, placebo-controlled trial. Clin J Pain 1998;14:227–231.
  5. Hart O, Mullee MA, Lewith G, Miller J: Double-blind, placebo-controlled, randomised clinical trial of homoeopathic arnica C30 for pain and infection after total abdominal surgery. J R Soc Med 1977;90:73–78.


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