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Table of Contents
Vol. 17, No. 6, 2000
Issue release date: 2000
Section title: Case Reports
Dig Surg 2000;17:627–631
(DOI:10.1159/000051973)

Malignant Peripheral Nerve Sheath Tumor of the Esophagus

Manger T. · Pross M. · Haeckel C. · Lippert H.
Departments of aSurgery and bPathology, Otto von Guericke University, Magdeburg, Germany

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Article / Publication Details

First-Page Preview
Abstract of Case Reports

Published online: 1/16/2001

Number of Print Pages: 5
Number of Figures: 7
Number of Tables: 1

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: http://www.karger.com/DSU

Abstract

Background: Sarcomas of the esophagus are rare representing 0.1–1.5% of all esophageal tumors. We report a case of malignant peripheral nerve sheath tumor (MPNST) of the esophagus in a 60-year-old woman. Methods: The diagnosis was made preoperatively on endoscopic biopsy and confirmed after tumor resection by immunohistochemistry as well as electron microscopy. The patient underwent abdominal-thoracicen bloc esophagectomy with mediastinal lymphadenectomy and intrathoracic esophagogastrostomy. Results: Our therapeutic concept for the first case of a high-grade MPNST (malignant schwannoma) of the esophagus resulted in a recurrence-free interval of 4 years. Conclusion: The therapy of choice was abdominal-thoracic en bloc esophagectomy with tumor-free resection margins and esophageal reconstruction with the stomach. After R0-resection we found no indication for adjuvant radio- and/or chemotherapy.


Article / Publication Details

First-Page Preview
Abstract of Case Reports

Published online: 1/16/2001

Number of Print Pages: 5
Number of Figures: 7
Number of Tables: 1

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: http://www.karger.com/DSU


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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