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Vol. 45, No. 1, 2001
Issue release date: January 2001
Section title: Original Paper
Eur Neurol 2001;45:28–33
(DOI:10.1159/000052085)

Experience of Severe Fatigue Long after Stroke and Its Relation to Depressive Symptoms and Disease Characteristics

van der Werf S.P. · van den Broek H.L.P. · Anten H.W.M. · Bleijenberg G.
aThe Netherlands Fatigue Research Group, Department of Medical Psychology, University Hospital Nijmegen, Nijmegen, bDepartment of Neurology, Maasland Hospital Sittard, Sittard, The Netherlands

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 1/5/2001

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 4

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE

Abstract

Although the experience of abnormal fatigue is recognised as a major disabling symptom in many chronic neurological diseases, little is known about the persistence of severe fatigue after an abrupt neurological incident like a stroke. Therefore, the objectives of this study were to test whether the experience of severe fatigue persists long after a stroke has occurred, and to assess the relation between experienced fatigue and levels of physical impairment and depression. Ninety stroke outpatients and 50 controls returned mailed questionnaires. Compared to age-matched controls, a significantly larger proportion (16 vs. 51%) of the stroke respondents experienced severe fatigue, while 20% of the patients and 16% of the controls had elevated depression symptom scores. The time which had elapsed since the stroke occurred could not explain levels of fatigue. In the control group, the number of depressive symptoms explained most of the variance in levels of fatigue, while impairment of locomotion explained most of the variance in the stroke group.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 1/5/2001

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 4

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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References

  1. MacHale S, O’Rourke S, Wardlaw J, Dennis M: Depression and its relation to lesion localization after stroke. J Neurol Neurosurg Psychiatry 1998;64:371–374.
  2. Paradiso S, Robinson R: Gender differences in poststroke depression. J Neuropsychiatry Clin Neurosci 1998;10:41–47.
  3. Angeleri F, Angeleri V, Foschi N, Giaquinto S, Nolfe G, Saginario A, Signorino M: Depression after stroke: An investigation through catamnesis. J Clin Psychiatry 1997;58:261–265.
  4. Kotila M, Numminen H, Waltimo O, Kaste M: Depression after stroke: Results of the FINNSTROKE Study. Stroke 1998;29:368–372.
  5. van der Werf S, Jongen P, Lycklama á Nijeholt G, Barkhof F, Hommes O, Bleijenberg G: Fatigue in multiple sclerosis: Interrelations between fatigue complaints, cerebral MRI abnormalities and neurological disability. J Neurol Sci 1998;160:164–170.
  6. Vercoulen J, Hommes O, Swanink C, Jongen P, Fennis J, Galama J, van der Meer J, Bleijenberg G: The measurement of fatigue in patients with multiple sclerosis: A multidimensional comparison with patients with chronic fatigue syndrome and healthy subjects. Arch Neurol 1996;53:642–649.
  7. Ingles JL, Eskes GA, Phillips SJ: Fatigue after stroke. Arch Phys Med Rehabil 1999;80:173–178.
  8. Beurskens A, Bultmann U, Kant I, Vercoulen J, Bleijenberg G, Swaen G: Fatigue among working people: Validity of a questionnaire measure. Occup Environ Med 2000;57:353–357.
  9. Stein P, Sliwinski M, Gordon W, Hibbard M: Discriminative properties of somatic and non-somatic symptoms for post stroke depression. Clin Neuropsychol 1996;10:141–148.
  10. Mohr D, Goodkin D, Likosky W, Beutler L, Gatto N, Langan M: Identification of Beck Depression Inventory items related to multiple sclerosis. J Behav Med 1997;20:407–414.
  11. Beck A, Guth D, Steer R, Ball R: Screening for major depression disorders in medical inpatients with the Beck Depression Inventory for Primary Care. Behav Res Ther 1997;35:785–791.
  12. Bergner M, Bobbit R, Carter W, Gilson B: The Sickness Impact Profile: Development and final revision of a health status measure. Med Care 1981;19:787–805.
  13. Vercoulen J, Bazelmans E, Swanink C, Fennis J, Galama J, Jongen P, Hommes O, van der Meer J, Bleijenberg G: Physical activity in chronic fatigue syndrome: Assessment and its role in fatigue. J Psychiatr Res 1998;31:661–673.
  14. Parra O, Arboix A, Bechich S, Garcia-Eroles L, Montserrat J, Lopez J, Ballester E, Guerra J, Sopena J: Time course of sleep-related breathing disorders in first-ever stroke or transient ischemic attack. Am J Respir Crit Care Med 2000;161:375–380.
  15. Nasr-Wyler A, Bouillanne O, Lalhou A, Goldenberg F, Bissery A, Piette F: Syndrome d’apnées du sommeil et accident vasculaire cérébral dans une population âgée. Rev Neurol (Paris) 1999;155:1057–1062.