- Responses, immunological
Rabies is a fatal encephalomyelitis. Most cases occur in developing countries and are transmitted by dogs. Because of their high cost, cell culture vaccines have not totally replaced the unsafe brain-derived vaccines which are still used in many developing countries. Moreover, there will be a need for vaccines against rabies-related viruses against which classical vaccines are not always effective. DNA vaccines would, therefore, be a valuable alternative for the production of cheaper rabies vaccines against a larger spectrum of viruses. In this review we report published data on DNA-based immunization with sequences encoding rabies and rabies-related virus antigens.
Copyright © 2001 S. Karger AG, Basel
Dr. Pierre Perrin
Laboratoire des Lyssavirus, Institut Pasteur
25, rue du Dr. Roux
F–75724 Paris (France)
Tel. +33 1 45 68 87 56, Fax +33 1 40 61 32 56, E-Mail firstname.lastname@example.org
Number of Print Pages : 10
Number of Figures : 4, Number of Tables : 1, Number of References : 35
Intervirology (International Journal of Basic and Medical Virology)
Founded 1973 by J.L. Melnick; continued by F. Rapp (1986–1990); M.J. Buchmeier and C.R. Howard (1991–1993)
Vol. 43, No. 4-6, Year 2000 (Cover Date: July-December 2000 (Released February 2001))
Journal Editor: Rüdiger W. Braun, Stuttgart
ISSN: 0300–5526 (print), 1423–0100 (Online)
For additional information: http://www.karger.com/journals/int
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