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Table of Contents
Vol. 34, No. 3, 2001
Issue release date: March 2001
Section title: Original Paper
Pediatr Neurosurg 2001;34:114–120
(DOI:10.1159/000056005)

Spina Bifida Outcome: A 25-Year Prospective

Bowman R.M. · McLone D.G. · Grant J.A. · Tomita T. · Ito J.A.
Division of Pediatric Neurosurgery, Children’s Memorial Hospital, Northwestern University Medical School, Chicago, Ill., USA

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 5/2/2001

Number of Print Pages: 7
Number of Figures: 4
Number of Tables: 1

ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)

For additional information: http://www.karger.com/PNE

Abstract

Background: Open spina bifida is the most complex congenital abnormality compatible with long-term survival. This report outlines the 20- to 25-year outcome for our original cohort of patients with a myelomeningocele treated in a nonselective, prospective manner. Methods: Of the initial 118 children, 71 patients were available for our most recent review. Nineteen patients have been lost to follow-up and 28 patients have died. Data were collected on: motor level, shunt status, education/employment, seizure history, mobility, bladder/bowel continence, tethered cord, scoliosis, latex allergy, posterior cervical decompression, tracheostomy and/or gastrostomy tube. Results: Mortality (24%) continues to climb into young adulthood. Eighty-six percent of the cohort have cerebrospinal fluid diversion, with 95% having undergone at least one shunt revision. Thirty-two percent have undergone a tethered cord release, with 97% having an improvement or stabilization in their preoperative symptoms. Forty-nine percent have scoliosis, with 43% eventually requiring a spinal fusion. Sixteen patients (23%) have had at least one seizure. Eighty-five percent are attending or have graduated from high school and/or college. More than 80% of young adults have social bladder continence. Approximately 1/3 of patients are allergic to latex, with 6 patients having experienced a life-threatening reaction. Conclusion: At least 75% of children born with a myelomeningocele can be expected to reach their early adult years. Late deterioration is common. One of the greatest challenges in medicine today is establishing a network of care for these adults with spina bifida.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 5/2/2001

Number of Print Pages: 7
Number of Figures: 4
Number of Tables: 1

ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)

For additional information: http://www.karger.com/PNE


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