- Hepatitis E virus
To identify the genotype of Vietnamese isolates of human hepatitis E virus (HEV), phylogenetic analysis was performed for the open reading frame (ORF) 1 and ORF2 nucleotide sequences of the viral genome. HEV was detected by RT-PCR in 9 out of 141 sera collected from patients with a diagnosis of acute sporadic hepatitis in Hanoi, Vietnam. All of them had sequences related most closely to genotype 4. In addition, the Vietnamese isolate had a single nucleotide insertion in the ORF 3 region, a characteristic reported for genotype 4 with the possible change of initiation of ORF 3 and ORF 2.
Copyright © 2002 S. Karger AG, Basel
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Minako Hijikata, MD
Department of Respiratory Diseases
Research Institute, International Medical Center of Japan
1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655 (Japan)
Tel. +81 3 3202 7181 (ext. 2875), Fax +81 3 3207 1038, E-Mail firstname.lastname@example.org
Received: Received: December 17, 2001
Accepted after revision: January 21, 2002
Number of Print Pages : 4
Number of Figures : 2, Number of Tables : 0, Number of References : 9
Intervirology (International Journal of Basic and Medical Virology)
Founded 1973 by J.L. Melnick; continued by F. Rapp (1986–1990); M.J. Buchmeier and C.R. Howard (1991–1993)
Vol. 45, No. 2, Year 2002 (Cover Date: March-April 2002 (Released July 2002))
Journal Editor: Rüdiger W. Braun, Stuttgart
ISSN: 0300–5526 (print), 1423–0100 (Online)
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