Journal Mobile Options
Table of Contents
Vol. 53, No. 4, 2002
Issue release date: August 2002
Gynecol Obstet Invest 2002;53:195–199
(DOI:10.1159/000064560)

Psychiatric Morbidity amongst Infertile Chinese Women Undergoing Treatment with Assisted Reproductive Technology and the Impact of Treatment Failure

Lok I.H. · Lee D.T.S. · Cheung L.P. · Chung W.S. · Lo W.K. · Haines C.J.
To view the fulltext, log in and/or choose pay-per-view option

Individual Users: Register with Karger Login Information

Please create your User ID & Password





Contact Information











I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in

Abstract

This is a prospective study to assess the psychiatric morbidity in Chinese infertile women who underwent treatments with assisted reproductive technology and also the impact of treatment failure. The 30-item General Health Questionnaire (GHQ) and the Beck Depression Inventory (BDI) were employed before and 3 weeks after the assisted reproductive technology treatment. Data from 372 patients who completed the questionnaires and failed the treatment were analyzed. Before treatment, 33% of the participants scored above the GHQ cutoff, and 8% had a BDI score of 20 or above, signifying moderate to severe depression. Following failed treatment, 43% scored above GHQ cutoff, and 8% had BDI scores 20 or above. The posttreatment GHQ and BDI scores were significantly higher than the corresponding scores at baseline (p < 0.001). About 13% of the participants reported self-harm ideas. The severity of depression following a failed treatment was positively associated with the duration of infertility (p < 0.05), but not with the posttreatment BDI scores, age, education, and number of previous treatment episodes. Our results show that one third of the women who sought infertility treatment had an impaired psychological well-being. Following failed treatment, there was a further deterioration in mental health, and about 10% of the participants were moderately to severely depressed. Proper psychological care and counseling should be an integral part of infertility management among the Chinese population.



Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

References

  1. Speroff L, Glass RH, Kase NG: Clinical Gynecologic Endocrinology and Infertility, ed 5. Baltimore, Williams & Wilkins, 1994.
  2. American Society for Reproductive Medicine (ASRM): News Release. Birmingham, ASRM, 1995.
  3. Mahlstedt PP: The psychological component of infertility. Fertil Steril 1985;43:335–346.

    External Resources

  4. Newton CR, Hearn MT, Yuzpe AA: Psychological assessment and follow-up after in vitro fertilization: Assessing the impact of failure. Fertil Steril 1990;54:879–886.
  5. Slade P, Emery J, Lieberman BA: A prospective, longitudinal study of emotions and relationships in in vitro fertilization treatment. Hum Reprod 1997;12:183–190.
  6. Leiblum SR, Kemmann E, Colburn D, Pasquale S, DeLisi AM: Unsuccessful in vitro fertilization: A follow-up study. J In Vitro Fert Embryo Transf 1987;4:46–50.

    External Resources

  7. Baram D, Tourtelot E, Muechler E, Huang KE: Psychosocial adjustment following unsuccessful in vitro fertilization. J Psychosom Obstet Gynaecol 1988;9:181–190.
  8. Lu YM: Psychosocial Status of Infertile Women in China: A Control Study; thesis Hunan Medical School, 1994.
  9. Xu L, Ke HX, He FF: Psychological aspects of infertile couples in China (in Chinese). Chung Hua Fu Chan Ko Tsa Chih 1994;29:232–234.
  10. Chan YF, O’Hay KM, Wong A, Wo WK, Ho PC, Tsoi MM: Psychological evaluation in an IVF/GIFT program in Hong Kong. J Reprod Infant Psychol 1989;7:67–77.
  11. Goldberg D: Manual of the General Health Questionnaire. Windsor, NFER-Nelson, 1978.
  12. Beck AT, Ward CH, Mendelson M: An inventory for measuring depression. Arch Gen Psychiatry 1961;4:561–571.
  13. Beck AT, Steer RA, Garbin MG: Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clin Psychol Rev 1988;8:77.

    External Resources

  14. Lee DTS, Wong CS, Cheung LP, Leung CM, Haines CJ, Chung TKH: Psychiatric morbidity following miscarriage: A prevalence study of Chinese women in Hong Kong. J Affect Disord 1997;43:63–68.
  15. Lee DTS, Yip SK, Chiu HFK, Chan KPM, Chau IOL, Leung CM: Detecting postnatal depression in Chinese women: Validation of the Chinese Edinburgh Postnatal Depression Scale. Br J Psychiatry 1998;172:433–437.
  16. Dikotter F: Imperfect Conceptions: Medical Knowledge, Birth Defects and Eugenics in China. New York, Columbia University Press, 1998, p 226.
  17. de Bary WM, Bloom I (eds): Sources of Chinese Tradition. New York, Columbia University Press, 1983, p 140.
  18. Van Balen F, Trimbos-Kemper TCM: Long term infertile couples: A study of their well-being. J Psychosom Obstet Gynaecol 1993;14:53–60.

    External Resources

  19. Ulbrich PM, Tremaglio-Coyle A, Llabre MM: Involuntary childlessness and marital adjustment: His and hers. J Sex Marital Ther 1990;16:147–158.
  20. Boivin J, Takefman JE, Tulandi T, Brender W: Reaction to infertility based on extent of treatment failure. Fertil Steril 1995;63:801–807.


Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50