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Vol. 48, No. 1, 2002
Issue release date: July 2002
Section title: Original Paper
Eur Neurol 2002;48:6–10
(DOI:10.1159/000064950)

Repetitive Transcranial Magnetic Stimulation for the Treatment of Chronic Pain – A Pilot Study

Rollnik J.D. · Wüstefeld S. · Däuper J. · Karst M. · Fink M. · Kossev A. · Dengler R.
Departments of aNeurology and Clinical Neurophysiology, bAnesthesiology, Pain Clinic, and cPhysical Medicine and Rehabilitation, Medical School of Hannover, Germany; dDepartment of Biophysics, Bulgarian Academy of Sciences, Sofia, Bulgaria

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 7/11/2002

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 1

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE

Abstract

Invasive electrical stimulation of the motor cortex has been reported to be of therapeutic value in pain control. We were interested whether noninvasive repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex might also act beneficially. Twelve patients with therapy-resistant chronic pain syndromes (mean age 51.3 ± 12.6, 6 males) were included in a pilot study. They were treated with rTMS of the corresponding motor cortex area for 20 min (20 Hz, 20 × 2 s trains, intensity 80% of motor threshold) and sham stimulation (sequence-controlled cross-over design). Some of the patients (6/6) had an analgesic effect, but for the whole group, the difference between active and sham stimulation did not reach a level of significance (active rTMS: mean VAS reduction –4.0 ± 15.6%; sham rTMS: –2.3 ± 8.8%). Further studies using different rTMS stimulation parameters (duration and frequency of rTMS) or stimulation sites (e.g. anterior cingulate gyrus) are strongly encouraged.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: 7/11/2002

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 1

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: http://www.karger.com/ENE


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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    External Resources

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