Vol. 11, No. 4, 2002
Issue release date: July–August 2002
Free Access
Neurosignals 2002;11:191–196
(DOI:10.1159/000065434)
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Analysis of Patterned Neuronal Impulses and Function of Neuregulin

Ozaki M.
Laboratory for Neural Architecture, Brain Science Institute, RIKEN, Saitama, Japan
email Corresponding Author


 goto top of outline Key Words

  • Neural plasticity
  • Neuregulin
  • Neuronal impulses

 goto top of outline Abstract

Compared to other cells, except neural cells, the biggest property of neural cells is to have a particular electrical activity in each cell itself. The activity that shows a specific pattern will carry different information as a history of each neural cell. At present, we have examined the roles of neural impulses and revealed that a synaptic plasticity can be controlled by different patterned neural acitivites, such as different frequencies or oscillation patterns. Even though neural cells have similar genetic backgrounds, different environments give cells different neural activities and finally different characters of cells. Current studies have revealed that a particular pattern of neural activity, e.g. frequency, could be effective in some diseases. In response to environmental changes occurring throughout development and adult life, the brain reorganizes itself by adjusting the pattern of activity. In some cases, a particular pattern of neural acitivity decides the neural fate and should be able to control brain function even in higher functions. In the future, in order to understand the role of activity patterns and mechanisms of fundamental information processing in the brain, it will be necessary that the meaning of patterns is explained from molecular, biological and morphological perspectives, i.e., not only with metaphysical ‘phenomena’, but also at a physical ‘material’ level.

Copyright © 2002 S. Karger AG, Basel


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    External Resources

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 goto top of outline Author Contacts

Miwako Ozaki, PhD
Laboratory for Neural Architecture, Brain Science Institute, RIKEN
Wako-shi, Saitama 351-0198 (Japan)
Tel. +81 48 462 1111, ext. 7264, Fax +81 48 467 5926
E-Mail mozaki@postman.riken.go.jp


 goto top of outline Article Information

Number of Print Pages : 6
Number of Figures : 3, Number of Tables : 1, Number of References : 35


 goto top of outline Publication Details

Neurosignals
Founded 1992 as ‘Biological Signals’ by S.F. Pang (1992–2001) continued as ‘Biological Signals and Receptors’ (1999–2001)

Vol. 11, No. 4, Year 2002 (Cover Date: July-August 2002)

Journal Editor: Nancy Y. Ip, Hong Kong
ISSN: 1424–862X (print), 1424–8638 (Online)

For additional information: http://www.karger.com/journals/nsg


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