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Table of Contents
Vol. 14, No. 3-4, 2002
Issue release date: October 2002
Section title: Original Paper
Cerebrovasc Dis 2002;14:228–233
(DOI:10.1159/000065667)

Cognitive Functions and Depression as Predictors of Poor Outcome 15 Months after Stroke

Pohjasvaara T. · Vataja R. · Leppävuori A. · Kaste M. · Erkinjuntti T.
aStroke Unit and bMemory Research Unit, Department of Clinical Neuroscience, and cDepartment of Psychiatry, Psychiatric Consultation Unit, Helsinki University Central Hospital, Helsinki, and dLohja District Hospital, Lohja, Finland

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 8/27/2001
Accepted: 2/21/2002
Published online: 10/25/2002

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 5

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED

Abstract

The prognostic predictors of poor outcome, as defined by death between 3 and 15 months and dependent living at 15 months, were examined in the Helsinki Stroke Aging Memory (SAM) study cohort. Death between 3 and 15 months was registered from the whole study group of 486 consecutive patients aged 55–85 years. Altogether 286 of the 486 patients went through a detailed follow-up examination both 3 and 15 months after stroke, including structured measures of emotion (Beck’s Depression Inventory, BDI), cognition (Mini-Mental State Examination, MMSE), dementia assessment according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-III), and handicap (Rankin scale, RS). The only independent correlate of death between 3 and 15 months was dependent living at 3 months (OR 2.6, 95% CI 1.2–5.8), which also had the most powerful association with dependent living at 15 months (OR 5.8, 95% CI 2.6–13.1). Also, both worsening in cognition (change in MMSE, OR for each point of worsening 1.2, 95% CI 1.1–1.3) and worsening of depression (change in BDI, OR for each point of worsening 1.1, 95% CI 1.02–1.12), between 3 and 15 months follow-up, had an independent effect on dependent living 15 months after ischemic stroke. This challenges the care and rehabilitation of these items even at the stable period after stroke.


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: 8/27/2001
Accepted: 2/21/2002
Published online: 10/25/2002

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 5

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: http://www.karger.com/CED


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