Intervirology 2002;45:318–327

Emerging Viruses: The Case ‘Hantavirus’

Ulrich R.a · Hjelle B.b · Pitra C.c · Krüger D.H.a
aInstitute of Virology, Humboldt University, Charité Medical School, Berlin, Germany; bDepartment of Pathology, University of New Mexico, Albuquerque,N.Mex., USA; cDepartment of Evolutionary Genetics, Institute for Zoo Biology and Wildlife Research, Berlin,Germany
email Corresponding Author

 goto top of outline Key Words

  • Hantavirus
  • Bunyaviridae
  • Emerging viruses
  • Rodents
  • Evolution
  • Pathogenesis
  • Vaccine

 goto top of outline Abstract

This review briefly summarises the recent knowledge about hantavirus infections and raises particular problems in hantavirus research that need further investigation. The following questions are addressed: (i) are hantaviruses distributed worldwide and what leads to new outbreaks, (ii) what is known about hantavirus evolution, (iii) how can hantavirus species be defined, (iv) what are the determinants of hantavirus pathogenesis in humans, and (v) what problems are associated with the development of new vaccines and antiviral therapeutics.

Copyright © 2003 S. Karger AG, Basel

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 goto top of outline Author Contacts

Dr. Detlev H. Krüger
Institute of Virology
Humboldt University, School of Medicine Charité
D–10098 Berlin (Germany)
Tel. +49 30 450 525092, Fax +49 30 450 525907, E-Mail

 goto top of outline Article Information

Number of Figures : 0, Number of Tables : 1, Number of References : 87

 goto top of outline Publication Details

Intervirology (International Journal of Basic and Medical Virology)
Founded 1973 by J.L. Melnick; continued by F. Rapp (1986–1990); M.J. Buchmeier and C.R. Howard (1991–1993)

Vol. 45, No. 4-6, Year 2002 (Cover Date: July-December 2002 (Released January 2003))

Journal Editor: Rüdiger W. Braun, Stuttgart
ISSN: 0300–5526 (print), 1423–0100 (Online)

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