To view the fulltext, please log in
To view the pdf, please log in
Background: Chronic anal fistulas are not rare conditions, however, the development of a carcinoma in a long-standing fistula-in-ano is rare. Methods: The case of a 77-year-old male with a large perianal mucinous adenocarcinoma arising in a long-standing fistula-in-ano is presented. Results: Perianal biopsy revealed mucinous adenocarcinoma. Abdominal CT, double contrast barium examination and flexible sigmoidoscopy revealed no other tumoral lesion in the colon and rectum. Conclusion: The patient underwent abdominoperineal resection including wide tumor excision on the gluteal region. The final reconstruction was performed by bilateral gracilis musculocutaneous flaps. Due to clinical and histopathological evidence it was thought that a curative resection had been performed. To date he is clinically disease free.
Copyright / Drug Dosage
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
- Marti L, Nussbaumer P, Breitbach T, Hollinger A: Perianal mucinous adenocarcinoma. A further reason for histological study of anal fistula or anorectal abscess. Chirurg 2001;72:573–577.
- Prioleau PG, Allen SM, Roberts T: Perianal mucinous adenocarcinoma. Cancer 1977;39:1295–1299.
- Cabrera A, Tsukada Y, Pichren J: Adenocarcinomas of the anal canal and perianal tissues. Ann Surg 1966;164:152–156.
- Dukes CE, Galvin C: Colloid carcinoma arising within fistulae in the ano-rectal region. Ann R Coll Surg Engl 1956;18:246–251.
- Onerheim RM: A case of perianal mucinous adenocarcinoma arising in a fistula-in-ano. A clue to the early pathologic diagnosis. Am J Clin Pathol 1988;89:809–812.
- Gordon PH: Anorectal abscesses and fistula-in-ano; in Gordon PH, Nivatvongs S (eds): Principles and Practice of Surgery for the Colon, Rectum and Anus, ed 3. St. Louis, Quality Medical, 1999, pp 281–282.
- Kline RJ, Spencer RJ, Harrison EG Jr: Carcinoma associated with fistula-in-ano. Arch Surg 1964;89:989–994.
- Nelson RL, Prasad ML, Abcarian H: Anal carcinoma presenting as a perirectal abscess or fistula. Arch Surg 1985;120:632–635.
- Getz SB, Ough YD, Patterson RB, Kovalcik PJ: Mucinous adenocarcinoma developing in a chronic anal fistula: Report of 2 cases and review of the literature. Dis Colon Rectum 1981;24:562–566.
- Kyzer S, Bayer I, Turani H, Chaimoff C: Verrucous squamous carcinoma as a complication of recurrent multiple perianal fistulae. Coloproctology 1985;7:104–106.