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Vol. 10, No. 1, 2003
Issue release date: February 2003
Section title: Original Article · Originalarbeit
Forsch Komplementärmed Klass Naturheilkd 2003;10:7–10
(DOI:10.1159/000069901)

Effects of One Week Juice Fasting on Lipid Metabolism: A Cohort Study in Healthy Subjects

Huber R. · Nauck M. · Lüdtke R. · Scharnagl H.
aAmbulanz für Naturheilverfahren / Abteilung Innere Medizin II, bAbteilung Klinische Chemie, Universitätsklinik Freiburg; cKarl und Veronica Carstens-Stiftung, Essen

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Article / Publication Details

First-Page Preview
Abstract of Original Article · Originalarbeit

Published online: 3/14/2003

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-4119 (Print)
eISSN: 1661-4127 (Online)

For additional information: http://www.karger.com/FOK

Abstract

Objective: We investigated the effects of a popular modified juice fasting program on lipid metabolism. Volunteers and Methods: 5 healthy, nonobese, male volunteers fasted for 8 days. Daily energy intake was limited to 150–300 kcal/d solely as carbohydrates (vegetable and fruit drinks). Physical activity was maintained as before. At baseline, on days 2, 3, and 8 during fasting, and on days 2 and 8 after fasting, serum lipids, lipoproteins, and insulin were investigated. Results: Juice fasting resulted in bi-phasic changes: Until day 2 and 3 triacylglycerols (TG), very low-density lipoprotein apolipoprotein B (VLDL apo B), and insulin decreased by 52, 51, and 65% respectively, while nonesterified fatty acids (NEFA), low-density lipoprotein (LDL) apo B, and LDL cholesterol increased by 363, 38, and 35%. Between day 3 and 8 NEFA increased; TG and insulin increased as well, but remained below baseline values, and LDL cholesterol normalized. After 8 days juice fasting significant changes (p < 0.05) compared to the baseline were found only for free cholesterol (-10%), phospholipids (-14%), apo AI (-9%), apo AII (-11%), insulin (-42%), C-peptide (-57%), and NEFA (+535%, p = 0.0001). Total cholesterol decreased by 9% (n.s.) after 8 days. One week after the ending of fasting all parameters returned to normal. Conclusion: Contrary to total fasting and fasting with limited physical activity, 8 days juice fasting without limitation of physical activity results in a decrease of free cholesterol and an only initial increase of LDL cholesterol. After 8 days insulin, TG, and VLDL are still lower than at baseline, however, they have increased compared to the initial phase, probably counterregulatory to a further increase of NEFA.


Article / Publication Details

First-Page Preview
Abstract of Original Article · Originalarbeit

Published online: 3/14/2003

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-4119 (Print)
eISSN: 1661-4127 (Online)

For additional information: http://www.karger.com/FOK


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