Journal Mobile Options
Table of Contents
Vol. 35, No. 4, 2003
Issue release date: July–August 2003

Experimental Study Using PTFE (Goretex) Patches for Replacement of the Oesophageal Wall

González Sáez L.A. · Arnal Monreal F. · Pita Fernández S. · Machuca Santa Cruz J.
To view the fulltext, log in and/or choose pay-per-view option

Individual Users: Register with Karger Login Information

Please create your User ID & Password

Contact Information

I have read the Karger Terms and Conditions and agree.

To view the fulltext, please log in

To view the pdf, please log in


Background: The purpose of this study was to evaluate tolerance and integration of expanded polytetrafluoroethylene patches used to replace loss of a fragment of the complete oesophageal wall in rats of the Wistar strain. Methods: The experiment was performed on 10 Wistar rats. Those surviving the experiment were killed 7–28 days after surgery. Results: None of these animals showed signs of peritonitis. The patch was not visible macroscopically. After examination under the microscope, we observed that the material had undergone phagocytosis by macrophages, and there was scar tissue covering the epithelium. Conclusion: It is possible to successfully suture a polytetrafluoroethylene patch to the oesophageal wall in Wistar rats as a prosthetic replacement of a wall fragment.

Copyright / Drug Dosage

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.


  1. Millikan KW, Pytynia KB: Repair of tracheal defect with Goretex graft during resection of carcinoma of the esophagus. J Surg Oncol 1997;66:134–137.
  2. Masciariello S, Purri P, Sanguiuolo P, Fimmano A, Antonelli B: Prosthetic materials for reparative surgery on the rat biliary tracts: Goretex and Dacron. Chir Patol Sper 1979;27:17–31.
  3. Harmon JW, Wright JA, Noel J, Cogan M: Fate of Dacron prostheses in the small bowel of rabbits. Surg Forum 1979;30:365–366.
  4. Purushotham AD, Carachi R, Gorham SD, French DA, Shivas AA: Use of a collagen coated Vicryl tube in reconstruction of the porcine esophagus. Eur J Pediatr Surg 1991;1:80–84.
  5. MacDonald A, Carachi R, Gibson A: A new oesophageal tube: Assessment of collagen/Vicryl composite membrane. J Pediatr Surg 1992;27:856–858.
  6. Freud E, Efrati I, Kidron D, Finally R, Mares AJ: Comparative experimental study of esophageal wall regeneration after prosthetic replacement. J Biomed Mater Res 1999;45:84–91.
  7. Castellon Pavón C, Landa García I, González Chamorro A, Hernandez Gallardo D, Moreno González E: Corrección de hernia inguinoescrotal gigante con apendicitis aguda. Cir Esp 1997;62:163–164.
  8. Jones JW, Jurkovich GJ: Polypropylene mesh closure of infected abdominal wounds. Am Surg 1989;55:73–76.
  9. Bleichrodt RP, Simmermacher RK, Van der Lei B, Schakenraad JM: Expanded polytetrafluoroethylene patch versus polypropylene mesh for the repair of contaminated defects of the abdominal wall. Surg Gynecol Obstet 1993;176:18–24.

Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50