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Vol. 18, No. 4, 2003
Issue release date: July–August 2003
Fetal Diagn Ther 2003;18:255–261

Correlation of Prenatal Ultrasound and Postnatal Outcome in Meconium Peritonitis

Shyu M.-K. · Shih J.-C. · Lee C.-N. · Hwa H.-L. · Chow S.-N. · Hsieh F.-J.
Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan

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Objectives: To study the relationship between prenatal ultrasound features and postnatal course of meconium peritonitis. Methods: Meconium peritonitis was diagnosed by prenatal ultrasound. Fetuses were treated by intrauterine paracentesis of ascites when indicated, and symptomatic newborns received surgery. Results: Totally 17 cases were enrolled. Prenatal ultrasound findings include abdominal calcification (16/17), fetal ascites (12/17), hydramnios (9/17), pseudocyst (7/17) and dilated bowel loop (6/17). Persistent ascites, pseudocyst or dilated bowel loop are most sensitive (92%) to predict postnatal surgery (p = 0.022). The survivors have a higher gestational age at birth (36.4 vs. 33.3 weeks, p = 0.008). Persistent ascites and postnatal persistent pulmonary hypertension of the newborns significantly correlate with neonatal mortality (p = 0.029 and 0.022). Conclusion: Prenatal ultrasound can predict the neonatal outcome in meconium peritonitis.

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  1. Lorimer WS, Ellis DG: Meconium peritonitis. Surgery 1966;60:470–475.
  2. Forouhar F: Meconium peritonitis. Pathology, evolution, and diagnosis. Am J Clin Pathol 1982;78:208–213.
  3. Dillard JP, Edwards DK, Leopold GR: Meconium peritonitis masquerading as fetal hydrops. J Ultrasound Med 1987;6:49–51.
  4. Foster MA, Nyberg DA, Mahony BS, Mack LA, Marks WM, Raabe RD: Meconium peritonitis: Prenatal sonographic findings and their clinical significance. Radiology 1987;165:661–665.
  5. Chalubinski K, Deutinger J, Bernaschek G: Meconium peritonitis: Extrusion of meconium and different sonographical appearances in relation to the stage of the disease. Prenat Diagn 1992;12:631–636.
  6. Graziani M, Bergami GL, Fasanelli S: Fibroadhesive meconium peritonitis: Ultrasonographic features. J Pediatr Gastroenterol Nutr 1994;18:241–243.
  7. Shyu MK, Chen CD, Hsieh FJ, Yau KI, Lin GJ, Lee ML: Intrauterine intervention in a case of recurrent meconium peritonitis. Prenat Diagn 1994;14:993–995.
  8. Dirkes K, Crombleholme TM, Craigo SD, Latchaw LA, Jacir NN, Harris BH, D’Alton ME: The natural history of meconium peritonitis diagnosed in utero. J Pediatr Surg 1995;30:979–982.
  9. Konje JC, de Chazal R, MacFadyen U, Taylor DJ: Antenatal diagnosis and management of meconium peritonitis: A case report and review of the literature. Ultrasound Obstet Gynecol 1995;6:66–69.
  10. Yang WT, Ho SS, Metreweli C: Case report: Antenatal sonographic diagnosis of meconium peritonitis and subsequent evolving meconium pseudocyst formation without peritoneal calcification. Clin Radiol 1997;52:477–479.
  11. Mayock DE, Hickok DE, Guthrie RD: Cystic meconium peritonitis associated with hydrops fetalis. Am J Obstet Gynecol 1982;142:704–705.
  12. Baxi LV, Yeh MN, Blanc WA, Schullinger JN: Antepartum diagnosis and management of in utero intestinal volvulus with perforation. N Engl J Med 1983;308:1519–1521.
  13. McGahan JP, Hanson F: Meconium peritonitis with accompanying pseudocyst: Prenatal sonographic diagnosis. Radiology 1983;148:125–126.
  14. Williams J 3rd, Nathan RO, Worthen NJ: Sonographic demonstration of the progression of meconium peritonitis. Obstet Gynecol 1984;64:822–826.
  15. Kamata S, Nose K, Ishikawa S, Usui N, Sawai T, Kitayama, Okuyama H, Imura K, Okada A: Meconium peritonitis in utero. Pediatr Surg Int 2000;16:377–379.
  16. Hsu CH, Jen LW, Huang FY, Chen MR, Kao HA, Ho WY, Yeh ML, Chang PY: Clinical observation of meconium peritonitis. Chung Hua Min Kuo Hsia Erh Ko I Hsueh Hui Tsa Chih 1990;31:214–220.
  17. Chang PY, Huang FY, Yeh ML, Sheu JC, Chen BF, Chen CC: Meconium ileus-like condition in Chinese neonates. J Pediatr Surg 1992;27:1217–1219.
  18. Pan EY, Chen LY, Yang JZ, Lee Z, Wang ZZ: Radiographic diagnosis of meconium peritonitis. A report of 200 cases including six fetal cases. Pediatr Radiol 1983;13:199–205.
  19. Ohmichi M, Kanai H, Kanzaki T, Matumoto K, Neki R, Chiba Y, Kamata S, Murata Y: Meconium peritonitis: Changes in fetal C-reactive protein and CA 125 levels in relation to stage of disease. J Ultrasound Med 1997;16:289–292.
  20. Langer JC, Adzick NS, Filly RA, Golbus MS, deLorimier AA, Harrison MR: Gastrointestinal tract obstruction in the fetus. Arch Surg 1989;124:1183–1186.
  21. Radner M, Vergesslich KA, Weninger M, Eilenberger M, Ponhold W, Pollak A: Meconium peritonitis: A new finding in rubella syndrome. J Clin Ultrasound 1993;21:346–349.
  22. Schild RL, Plath H, Thomas P, Schulte-Wissermann H, Eis-Hubinger AM, Hansmann M: Fetal parvovirus B19 infection and meconium peritonitis. Fetal Diagn Ther 1998;13:15–18.
  23. Tibboel D, Gaillard JL, Molenaar JC: The importance of mesenteric vascular insufficiency in meconium peritonitis. Hum Pathol 1986;17:411–416.
  24. Nancarrow PA, Mattrey RF, Edwards DK, Skram C: Fibroadhesive meconium peritonitis: In utero sonographic diagnosis. J Ultrasound Med 1985;4:213–215.
  25. Donnison AB, Shwachman H, Gross RE: A review of 164 children with meconium ileus seen at the Children’s Hospital Medical Center, Boston. Pediatrics 1966;37:833–850.
  26. Bergmans MG, Merkus JM, Baars AM: Obstetrical and neonatological aspects of a child with atresia of the small bowel. J Perinat Med 1984;12:325–332.

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