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Correlation of Prenatal Ultrasound and Postnatal Outcome in Meconium Peritonitis

Shyu M.-K. · Shih J.-C. · Lee C.-N. · Hwa H.-L. · Chow S.-N. · Hsieh F.-J.
Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan Fetal Diagn Ther 2003;18:255–261 (DOI:10.1159/000070806)


Objectives: To study the relationship between prenatal ultrasound features and postnatal course of meconium peritonitis. Methods: Meconium peritonitis was diagnosed by prenatal ultrasound. Fetuses were treated by intrauterine paracentesis of ascites when indicated, and symptomatic newborns received surgery. Results: Totally 17 cases were enrolled. Prenatal ultrasound findings include abdominal calcification (16/17), fetal ascites (12/17), hydramnios (9/17), pseudocyst (7/17) and dilated bowel loop (6/17). Persistent ascites, pseudocyst or dilated bowel loop are most sensitive (92%) to predict postnatal surgery (p = 0.022). The survivors have a higher gestational age at birth (36.4 vs. 33.3 weeks, p = 0.008). Persistent ascites and postnatal persistent pulmonary hypertension of the newborns significantly correlate with neonatal mortality (p = 0.029 and 0.022). Conclusion: Prenatal ultrasound can predict the neonatal outcome in meconium peritonitis.


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