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Table of Contents
Vol. 39, No. 1, 2003
Issue release date: July 2003
Pediatr Neurosurg 2003;39:50–54
(DOI:10.1159/000070881)

Cortical Ependymoma

A Case Report and Review

Lehman N.L. · Jorden M.A. · Huhn S.L. · Barnes P.D. · Nelson G.B. · Fisher P.G. · Horoupian D.S.
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Abstract

The authors report a rare case of a cortical ependymoma in a 10-year-old boy. The patient presented with complex partial seizures and a well-circumscribed, right frontal cortical mass. Routine microscopy showed a glial tumor with diverse histologic features. Immunohistochemistry and electron microscopy were required to establish the definitive diagnosis of cortical ependymoma. Cortical-based pediatric brain tumors range from World Health Organization grade I to III lesions and require significantly different treatment and follow-up. This case illustrates the importance of establishing an accurate neuropathologic tissue diagnosis of all pediatric cortical tumors.



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References

  1. Burger PC, Scheithauer BW: Tumors of the central nervous system; in Atlas of Tumor Pathology. Washington, Armed Forces Institute of Pathology, 1994, pp 77–225.
  2. Fujimoto K, Ohnishi H, Koshimae N, Ida Y, Kanemoto Y, Motoyama Y, Tsujimoto M, Takemura K: Brain surface clear cell ependymoma: Case report (in Japanese). No Shinkei Geka 1999;27:843–846.
  3. Sato Y, Ochiai H, Yamakawa Y, Nabeshima K, Asada Y, Hayashi T: Brain surface ependymoma. Neuropathology 2000;20:315–318.
  4. Oppenheim JS, Strauss RC, Mormino J, Sachdev VP, Rothman AS: Ependymomas of the third ventricle. Neurosurgery 1994;34:350–352.
  5. Vernet O, Farmer JP, Meagher-Villemure K, Montes JL: Supratentorial ectopic ependymoma. Can J Neurol Sci 1995;22:316–319.
  6. Saito T, Oki S, Mikami T, Kwamoto Y, Yamaguchi S, Kuwamoto K, Hayashi Y: Supratentorial ectopic ependymoma: A case report (in Japanese). No Shinkei Geka 1999;27:1139–1144.
  7. Youkilis AS, Park P, McKeever PE, Chandler WF: Parasagittal ependymoma resembling falcine meningioma. AJNR Am J Neuroradiol 2001;22:1105–1108.
  8. Morantz RA, Kepes JJ, Batnitzky S, Masterson BJ: Extraspinal ependymomas. Report of three cases. J Neurosurg 1979;51:383–391.
  9. Wilson RW, Moran CA: Primary ependymoma of the mediastinum: A clinicopathologic study of three cases. Ann Diagn Pathol 1998;2:293–300.
  10. Guerrieri C, Jarlsfelt I: Ependymoma of the ovary. A case report with immunohistochemical, ultrastructural, and DNA cytometric findings, as well as histogenic considerations. Am J Surg Pathol 1993;17:623–632.
  11. Vinchon M, Soto-Ares G, Riffaud L, Ruchoux MM, Dhellemmes P: Supratentorial ependymoma in children. Pediatr Neurosurg 2001;34:77–87.
  12. Palma L, Celli P, Mariottini A, Zalaffi A, Schettini G: The importance of surgery in supratentorial ependymomas. Long-term survival in a series of 23 cases. Childs Nerv Syst 2000;16:170–175.
  13. Needle MN, Goldwein JW, Grass J, Cnaan A, Bergman I, Molloy P, Sutton L, Zhao H, Garvin JH Jr, Phillips PC: Adjuvant chemotherapy for the treatment of intracranial ependymoma in childhood. Cancer 1997;80:341–347.
  14. Daneyemez M, Can C, Izci Y, Beduk A, Timuckaynak E: The tanycytic ependymoma of the lateral ventricle: Case report. Minim Invasive Neurosurg 1999;42:201–203.
  15. Pimentel J, Kepes JJ, Moura Nunes JF, Bentes C, Miguens J, Antunes JL: Supratentorial giant cell ependymoma. Clin Neuropathol 2001;20:31–37.
  16. Goel R, Gumerlock MK, Leech RW, Brumback R, Adesina AM: Intracerebral myxopapillary ependymoma: A case report. J Neuropathol Exp Neurol 2001;60:519.
  17. Min KW, Scheithauer BW: Clear cell ependymoma: A mimic of oligodendroglioma: Clinicopathologic and ultrastructural considerations. Am J Surg Pathol 1997;21:820–826.
  18. Hirato J, Nakazato Y, Iijima M, Yokoo H, Sasaki A, Yokota M, Ono N, Hirato M, Inoue H: An unusual variant of ependymoma with extensive tumor cell vacuolization. Acta Neuropathol 1997;93:310–316.
  19. Langford LA, Barre GM: Tanycytic ependymoma. Ultrastruct Pathol 1997;21:135–142.
  20. Daumas-Duport C, Sheithauer BW, Chodkiewicz JP, Laws ER Jr, Vedrenne C: Dysembryoplastic neuroepithelial tumor: A surgically curable tumor of young patients with intractable partial seizures. Report of thirty-nine cases. Neurosurgery 1988;23:545–556.
  21. Ostertun B, Wolf HK, Campos MG, Matus C, Solymosi L, Elger CE, Schramm J, Schild HH: Dysembryoplastic neuroepithelial tumors: MR and CT evaluation. AJNR Am J Neuroradiol 1996;17:419–430.
  22. Rubinstein LJ, Herman MM: The astroblastoma and its possible cytogenic relationship to the tanycyte. An electron microscopic, immunohistochemical, tissue- and organ-culture study. Acta Neuropathol (Berl) 1989;78:472–483.
  23. Brat DJ, Hirose Y, Cohen KJ, Feuerstein BG, Burger PC: Astroblastoma: Clinicopathologic features and chromosomal abnormalities defined by comparative genomic hybridization. Brain Pathol 2000;10:342–352.
  24. Port JD, Brat DJ, Burger PC, Pomper MG: Astroblastoma: Radiologic-pathologic correlation and distinction from ependymoma. AJNR Am J Neuroradiol 2002;23:243–247.


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