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Vol. 65, No. 5, 2003
Issue release date: September–October 2003
ORL 2003;65:300–302

Recurrent Ceruminous Adenocarcinoma of the External Auditory Canal

Tzagaroulakis A. · Pasxalidis J. · Papadimitriou N. · Boussiotou A. · Nikolopoulos T. · Korres S. · Ferekidis E.
Department of Otolaryngology, School of Medicine, University of Athens, and Department of Pathology, Hippokration Hospital, Athens, Greece

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Ceruminous adenocarcinoma is a rare malignant neoplasm of the glandular structures of the external auditory canal. The true incidence and behavior of these rare tumors are still unclear due to confusing terminology, classification and histological definitions. Therefore, the ENT surgeon faces major difficulties in choosing the method of management – conservative or more radical surgery – with the addition or not of radiotherapy. We report a 57-year-old male patient with a recurrence of a previously excised (maybe partially) and irradiated ceruminous adenocarcinoma of the right external auditory canal. Aggressive surgery was considered as the treatment of choice. However, the patient refused this approach and, as a consequence, a conservative excision was performed but with histologically confirmed healthy margins. To our surprise, the patient showed an excellent response and he is disease free 3 years following the last operation. Although recurrences usually occur within months after inadequate management, some may happen even 7 years post treatment. Therefore, routine long-term follow-up was advised.

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  1. Mills GR, Douglas-Jones T, Gareth Williams R: ‘Ceruminoma’ – A defunct diagnosis. J Lar 1995;109:180–188.
  2. Welti CV, Pardo V, Milland M, Gerston K: Tumors of ceruminous glands. Cancer 1972;29:1169–1178.
  3. Thawley ES, Panje RW, Batsakis GJ, Lindberg DR: Comprehensive Management of Head and Neck Tumors. Tumors of the Ear, ed 2. Philadelphia, Saunders, 1999.
  4. Hicks GW: Tumors arising from glandular structures of the external auditory canal. Laryngoscope 1983;93:326–340.
  5. Mansour P, George KM, Pahor LA: Ceruminous gland tumors: A reappraisal. J Laryngol Otol 1992;106:727–732.
  6. Haraguchi H, Hentona H, Tanaka H, Komatuzaki A: Pleomorphic adenoma of the external auditory canal: A case report and review of the literature. J Laryngol Otol 1996;110:52–56.
  7. Sharma SH, Meorkamal ZM, Zainol H, Dharap SA: Eccrine cylindroma of the ear canal – Report of a case. J Laryngol Otol 1994;108:706–709.
  8. Goodwin JW, Jesse HR: Malignant neoplasms of the external auditory canal and temporal bone. Arch Otolaryngol 1980;106:675–679.
  9. Turner HA, Carter H, Neptune WB: Pulmonary metastases from ceruminous adenocarcinoma (cylindroma) of external auditory canal. Cancer 1971;28:775–780.
  10. Ahmed MSG, Nath Deb KD: Ceruminous gland tumor (a case report). J Laryngol Otol 1988;102:346–349.
  11. Canker V, Crowley H: Tumors of ceruminous glands. Cancer 1964;17:67–75.
  12. Dehner LP, Chen KTK: Primary tumors of the external and middle ear. Arch Otolaryngol 1980;106:13–19.

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