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Vol. 17, No. 4, 2004
Issue release date: June 2004

Recognition of Emotion in the Frontal and Temporal Variants of Frontotemporal Dementia

Rosen H.J. · Pace-Savitsky K. · Perry R.J. · Kramer J.H. · Miller B.L. · Levenson R.W.
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Abstract

Recent studies have suggested that the frontal and temporal variants of frontotemporal dementia (fvFTD and tvFTD) are both associated with impairments in emotional processing. However, the degree and type of emotional processing deficits in the two syndromes have not been previously compared. We used the Florida Affect Battery to examine recognition of facial expressions of emotion in fvFTD and tvFTD patients who have no evidence of visual perceptual difficulties for faces. In general, both groups were impaired at recognizing emotions compared with age-matched controls. In tvFTD, this deficit was limited to emotions with a negative valence (sadness, anger, fear), while fvFTD patients showed impairment for positive valence (happiness) as well. These results suggest that damage to frontal lobe regions in FTD may lead to more profound impairment in recognition of emotion than when damage is more limited to the temporal lobe.



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References

  1. Bozeat S, Gregory CA, Ralph MA, Hodges JR: Which neuropsychiatric and behavioural features distinguish frontal and temporal variants of frontotemporal dementia from Alzheimer’s disease? J Neurol Neurosurg Psychiatry 2000;69:178–186.
  2. Snowden JS, Bathgate D, Varma A, Blackshaw A, Gibbons ZC, Neary D: Distinct behavioural profiles in frontotemporal dementia and semantic dementia. J Neurol Neurosurg Psychiatry 2001;70:323–332.
  3. Liu W, Miller BL, Kramer JH, Rankin K, Wyss-Coray C, Gearhart R, Phengrasamy L, Weiner M, Rosen HJ: Behavioral disorders in the frontal and temporal variants of frontotemporal dementia. Submitted.
  4. Lavenu I, Pasquier F, Lebert F, Petit H, Van der Linden M: Perception of emotion in frontotemporal dementia and Alzheimer disease. Alzheimer Dis Assoc Disord 1999;13:96–101.
  5. Keane J, Calder AJ, Hodges JR, Young AW: Face and emotion processing in frontal variant frontotemporal dementia. Neuropsychologia 2002;40:655–665.
  6. Rosen HJ, Perry RJ, Murphy J, Kramer JH, Mychack P, Schuff N, Weiner M, Levenson RL, Miller BL: Emotion comprehension in the temporal variant of frontotemporal dementia. Brain 2002;125:2286–2295.
  7. Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller BL, Cummings J, Benson DF: Frontotemporal lobar degeneration: A consensus on clinical diagnostic criteria. Neurology 1998;51:1546–1554.
  8. Rosen HJ, Gorno-Tempini ML, Goldman WP, Perry RJ, Schuff N, Weiner M, Feiwell R, Kramer JH, Miller BL: Patterns of brain atrophy in frontotemporal dementia and semantic dementia. Neurology 2002;58:198–208.
  9. Bowers D, Blonder L, Heilman K: The Florida Affect Battery. Gainesville, Center for Neuropsychological Studies, University of Florida, 1992.
  10. Adolphs R, Tranel D, Damasio H, Damasio A: Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala. Nature 1994;372:669–672.
  11. Scott SK, Young AW, Calder AJ, Hellawell DJ, Aggleton JP, Johnson M: Impaired auditory recognition of fear and anger following bilateral amygdala lesions. Nature 1997;385:254–257.
  12. Adolphs R, Tranel D, Hamann S, Young AW, Calder AJ, Phelps EA, Anderson A, Lee GP, Damasio AR: Recognition of facial emotion in nine individuals with bilateral amygdala damage. Neuropsychologia 1999;37:1111–1117.
  13. Anderson AK, Spencer DD, Fulbright RK, Phelps EA: Contribution of the anteromedial temporal lobes to the evaluation of facial emotion. Neuropsychology 2000;14:526–536.
  14. Boccardi M, Pennanen C, Laakso MP, Testa C, Geroldi C, Soininen H, Frisoni GB: Amygdaloid atrophy in frontotemporal dementia and Alzheimer’s disease. Neurosci Lett 2002;335:139–143.
  15. Hornak J, Bramham J, Rolls ET, Morris RG, O’Doherty J, Bullock PR, Polkey CE: Changes in emotion after circumscribed surgical lesions of the orbitofrontal and cingulate cortices. Brain 2003;126:1691–1712.
  16. Delis DC, Kramer JH, Kaplan E, Ober BA: California Verbal Learning Test, ed 2. San Antonio, The Psychological Corporation, 2000.
  17. Kaplan E, Goodglass H, Wintraub S: The Boston Naming Test. Philadelphia, Lea and Febiger, 1983.


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