Open Access Gateway
Med Princ Pract 2004;13:234–236
(DOI:10.1159/000078322)

Giant Cell Arteritis of the Breast

Anim J.T.a · van Herk E.J.b
aDepartment of Pathology, Faculty of Medicine, Kuwait University, bDepartment of Surgery, Al-Hadi Clinic, Kuwait
email Corresponding Author


 goto top of outline Key Words

  • Breast
  • Giant cell arteritis
  • Mastectomy

 goto top of outline Abstract

Objective: To report a rare case of giant cell arteritis of the breast in a 56-year-old woman. Clinical Presentation and Intervention: The patient presented with tenderness in the upper outer quadrant of the left breast, in the absence of any constitutional symptoms. A diagnosis of giant cell arteritis was made only after surgical wedge excision of the affected breast quadrant. She returned 6 weeks later with tenderness in the upper inner medial quadrant of the same breast, with a raised erythrocyte sedimentation rate. She has since been referred to the rheumatologist for further management. Conclusion: The diagnosis of giant cell arteritis of the breast was made only after pathological examination of the excised breast tissue. This study focused attention on the need to be aware of systemic conditions that may present as localised lesions of the breast and to maintain a high index of clinical suspicion in order to adequately investigate them and perhaps avoid unnecessary radical surgical intervention such as mastectomy.

Copyright © 2004 S. Karger AG, Basel


 goto top of outline References
  1. McKendry RJR, Guindi M, Hill DP: Giant cell arteritis (temporal arteritis) affecting the breast: Report of two cases and review of published reports. Ann Rheum Dis 1990;49:1001–1004.
  2. Lau Y, Mak YF, Hui PK, Ahchong AK: Giant cell arteritis of the breast. Aust NZ J Surg 1996;66:259–261.
  3. Cook DJ, Bensen WG, Carroll JJ, Joshi S: Giant cell arteritis of the breast. CMAJ 1988;139:513–515.
  4. Clement PB, Senges H, How AR: Giant cell arteritis of the breast: Case report and literature review. Hum Pathol 1987;18:1186–1189.
  5. Chaitin B, Kohout ND, Goldman RL: Focal arteritis of the breast. Angiology 1981;32:334–337.
  6. Dega FJ, Hunder GG: Vasculitis of the breast. Arthritis Rheum 1974;17:973–976.
  7. Susmano A, Roseman D, Haber MH: Giant cell arteritis of the breast: A unique syndrome. Arch Intern Med 1990;150:900–904.
  8. Potter BT, Housley E, Thomson D: Giant cell arteritis mimicking carcinoma of the breast. Br Med J 1981;282:1665–1666.
  9. Trueb RM, Scheidegger EP, Pericin M, Singh A, Hoffmann U, Sauvant G, Burg G: Periarteritis nodosa presenting as a breast lesion: Report of a case and review of the literature. Br J Dermatol 1999;141:1117–1121.
  10. Pappo I, Beglaibter N, Amir G: Mammary arteritis mimicking cancer. Eur J Surg 1992;158:191–193.
  11. Ng WF, Chow LTC, Lam PWY: Localized polyarteritis nodosa of breast – Report of two cases and review of the literature. Histopathology 1993;23:535–539.
  12. Deininger HK: Wegener granulomatosis of the breast. Radiology 1985;154:59–60.
  13. Jordan JM, Rowe WT, Allen NB: Wegener’s granulomatosis involving the breast. Am J Med 1987;83:159–164.

 goto top of outline Author Contacts

Dr. J.T. Anim
Department of Pathology, Faculty of Medicine
Kuwait University, PO Box 24923
13110 Safat (Kuwait)


 goto top of outline Article Information

Received: January 22, 2003
Revised: June 22, 2003
Number of Print Pages : 3
Number of Figures : 2, Number of Tables : 0, Number of References : 13


 goto top of outline Publication Details

Medical Principles and Practice
A Publication of the Academic Publications Council

Vol. 13, No. 4, Year 2004 (Cover Date: July-August 2004)

Journal Editor: Farida Al Awadi, Kuwait
ISSN: 1011–7571 (print), 1423–0151 (Online)

For additional information: http://www.karger.com/mpp


Open Access License / Drug Dosage / Disclaimer

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in goverment regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.