Table of Contents
To view the fulltext, log-in or choose pay-per-view options:
Get Access

Family History and Risk of Hair Loss

Chumlea W.C.a · Rhodes T.b · Girman C.J.b · Johnson-Levonas A.c · Lilly F.R.W.d · Wu R.a · Guo S.S.a
aDepartment of Community Health, Wright State University School of Medicine, Dayton, Ohio, bDepartment of Epidemiology, Merck Research Laboratories, West Point, Pa., cDepartment of Endocrinology and Metabolism, Merck Research Laboratories, Rahway, N.J., and dDepartment of Community Planning, Hanover Hospital, Hanover, Pa., USA Dermatology 2004;209:33–39 (DOI:10.1159/000078584)


Introduction: The genetic basis of androgenetic alopecia (AGA) is well accepted in the medical community and among the general population. However, rigorous studies investigating the familial basis of AGA are lacking. The purpose of the current study was to explore the relationship between family history and expression of AGA in a sample of men from the general community. Methods: Hair loss was assessed by an independent observer trained by an expert dermatologist using the Norwood/Hamilton classification scale and a 7-point global description of hair loss. Men were classified into two groups, one as having little or no hair loss and the other having hair loss. The family history of hair loss in parents and grandparents was assessed by subject self-report. Results: Adjusting for age, men whose fathers had hair loss were 2.5 times as likely to have had some level of hair loss compared to men whose fathers had no hair loss (95% CI: 1.3–4.9). Likewise, men whose fathers had hair loss were twice as likely to have hair loss than men whose fathers had no hair loss even after adjusting for age (OR = 2.1, 95% CI: 1.2–3.7 and OR = 2.5, 95% CI: 1.4–4.7 for Norwood/Hamilton and global description of hair loss assessments, respectively). Conclusion: Results suggest that the probability of male pattern hair loss is dependent on family history and age. Hair loss in a man’s father also appears to play an important role in increasing a man’s risk of hair loss, either in conjunction with a history of hair loss in the mother or hair loss in the maternal grandfather.


Individual Users: Register with Karger Login Information

Please create your User ID & Password

Contact Information

I have read the Karger Terms and Conditions and agree.

Pay-per-View Options
Direct payment This item at the regular price: USD 38.00
Payment from account With a Karger Pay-per-View account (down payment USD 150) you profit from a special rate for this and other single items.
This item at the discounted price: USD 26.50