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Vol. 73, No. 1, 2004
Issue release date: July 2004

Mixed Germ Cell Tumor after Bilateral Orchidopexy in Persistent Müllerian Duct Syndrome with Transverse Testicular Ectopia

Manassero F. · Cuttano M.G. · Morelli G. · Salinitri G. · Spurio M. · Selli C.
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Abstract

The persistent müllerian duct syndrome is characterized by the retention of müllerian derivatives (fallopian tubes, uterus) in patients otherwise normally virilized, usually with cryptorchidism or an inguinal hernia. Very rarely, this syndrome is associated with transverse testicular ectopia , which designates the condition when both testes descend through the same inguinal canal into the same scrotal sac. We report on a patient with both conditions, who had T1N2M0 scrotal mixed germ cell tumor of the testis (teratoma and embryonal carcinoma), 18 years after bilateral orchidopexy. The literature concerning this uncommon association is reviewed.



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References

  1. Berkmen F: Persistent müllerian duct syndrome with or without transverse testicular ectopia and testis tumours. Br J Urol 1997;79:122–126.
  2. Josso N, Picard JY, Imbeaud S, Carré-Eusèbe D, Zeller J, Adamsbaum C: The persistent müllerian duct syndrome: A rare cause of cryptorchidism. Eur J Pediatr 1993;152(suppl 2):S76-S78.
  3. Berkmen F, Alagol H: Germinal cell tumors of the testis in cryptorchids. J Exp Clin Cancer Res 1998;17:409–412.
  4. Eastham JA, McEvoy K, Sullivan R, Chandrasoma P: A case of simultaneous bilateral nonseminomatous testicular tumors in persistent müllerian duct syndrome. J Urol 1993;148:407–408.
  5. Wu H-C, Chen J-H, Lu H-F, Shen W-C: Persistent müllerian duct syndrome with seminoma: CT findings. AJR 2000;174:102–104.
  6. Duenas A, Saldivar C, Castillero C, Flores G, Martinez P, Jimenez M: A case of bilateral seminoma in the setting of persistent müllerian duct syndrome. Rev Invest Clin 2001;53:193–196.
  7. Bucci S, Liguori G, Buttazzi L, Bussani R, Trombetta C: Bilateral testicular carcinoma in patient with the persistent müllerian duct syndrome. J Urol 2002;167:1790.


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