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Vol. 42, No. 3, 1999
Issue release date: October 1999
Eur Neurol 1999;42:132–135

Coeliac Disease Presenting with Neurological Disorders

Luostarinen L. · Pirttilä T. · Collin P.
Departments of aNeurology and bInternal Medicine, Tampere University Hospital, cMedical School and dDepartment of Neurology, University of Tampere, eDepartment of Neurology, Kuopio University Hospital, Kuopio, Finland

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It is well known that coeliac disease may be associated with various neurological manifestations. We have had a high index of suspicion of coeliac disease during recent years in our neurological clinic. As a result 10 (7%) out of 144 of our new coeliac patients were detected because of neurological symptoms. The most common neurological manifestations were neuropathy, memory impairment and cerebellar ataxia. In these patient groups screening for coeliac disease with serological antibody tests helps to find patients who may suffer from this disease.

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  1. Mäki M, Collin P: Coeliac disease. Lancet 1997;349:1755–1759.
  2. Collin P, Reunala T, Pukkala E, Laippala P, Keyriläinen O, Pasternack A: Coeliac disease: Associated disorders and survival. Gut 1994;35:1215–1218.
  3. Bode S, Hassager C, Gudmand-Hoyer E, Christiansen C: Body composition and calcium metabolism in adult coeliac disease. Gut 1991;32:1342–1345.
  4. Cooper BT, Read AE: Coeliac disease and lymphoma. Q J Med 1987;63:269–274.

    External Resources

  5. Collin P, Salmi J, Hällström O, Reunala T, Pasternack A: Autoimmune thyroid disorders and coeliac disease. Eur J Endocrinol 1994;130:137–140.
  6. Collin P, Salmi J, Hällström O, Oksa H, Oksala H, Mäki M, Teunala T: High frequency of coeliac disease in adult patients with type I diabetes. Scand J Gastroenterol 1989;24:81–84.

    External Resources

  7. Cooke WT, Smith T: Neurological disorders associated with adult coeliac disease. Brain 1966;89:683–722.
  8. Chapman RWG, Laidlow JM, Colin-Jones D: Increased prevalence of epilepsy in coeliac disease. BMJ 1978;2:250–251.
  9. Finelli PF, McEntee WJ, Ambler M, Kestenbaum D: Adult celiac disease presenting as cerebellar syndrome. Neurology 1980;30:245–249.

    External Resources

  10. Hadjivassiliou M, Chattopadhyay AK, Davies-Jones GA, Gibson A, Grünewald RA, Lobo AJ: Neuromuscular disease as a presenting feature of coeliac disease. J Neurol Neurosurg Psychiatry 1997;63:770–775.
  11. Gobbi G, Bouquet F, Greco L, Lambertini A, Tassinari CA, Ventura A, Zaniboni MG: Coeliac disease, epilepsy and cerebral calcifications. Lancet 1992;340:439–443.
  12. Hadjivassiliou M, Gibson A, Davies-Jones GAB, Lobo JA, Stephenson TJ, Milford-Ward A: Does cryptic gluten sensitivity play a part in neurological illness? Lancet 1996;347:369–371.
  13. Collin P, Pirttilä T, Nurmikko T, Somer H, Erilä T, Keyriläinen O: Celiac disease, brain atrophy, and dementia. Neurology 1991;41:372–375.
  14. Collin P, Reunala T, Rasmussen S, Kyrönpalo S, Pehkonen E, Laippala P, Mäki M: High incidence and prevalence of adult coeliac disease: Augmented diagnostic appraoch. Scand J Gastroenterol 1997;32:1129–1133.
  15. Hadjivassiliou M, Grunewald RA, Chattopadhyay AK, Davies-Jones GAB, Gibson A, Jarrat JA, Kandler RH, Lobo A, Powell T, Smith CML: Clinical, radiological, neurophysiological, and neuropathological characteristics of gluten ataxia. Lancet 1998;352:1582–1585.

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